Desonide

Chemical name

(11бета,16альфа))-11,21-Диг��дрокси-16,17-[(1-метилэти лиден)бис (окси)прегна-1,4-диен-3,20 -дион

Gross

C24-H32-O6

Characteristics

Glukokortikoid local Primenenia.nebolshie plates powder or white, or almost white, odourless. Rat in methanol, nerastvorim almost in the water.

Of drugs

The drugs - противовоспалительно е local, protiwallergicescoe, sossoudossouerveshchee. Induces education lipokortinov inhibiting activity fosfolipaza A_2 inhibits the synthesis of GHGs and LT. Decreases blood pressure, chemotaxis, contributes to the stabilization lizosom.

Indications

Inflammatory diseases of the front segment of the eye and its appendages : allergic conjunctivitis, exposed blefarit, episclerit, recurrent irit, iridotsyklit (rear segment of the eye); Postoperative trauma and eye inflammation; Thermal and chemical destruction cornea.

Restrictions on the use of

Pregnancy, breast feeding, child age (safety and efficacy of the use of children to be determined).

Pregnancy and lactation

When pregnancy and breast-feeding is possible only by strict conditions and under the supervision of a physician.

Contraindications

Hypersensitivity, increased inner pressure, conjunctivitis with ulcerative keratitom (including in the early stages, with a positive test with flwarestseinom), viral diseases cornea (including by Herpes simplex, in the izgyazwlenia), tuberculosis eye Mycobacterium eye truly oftalmia, eight conjunctivitis, and eight gerpeticeski blefarit, barley.

Side-Effects

Local reactions : pricking or burning sensation in the eye; In the long-term use Improvement vnutriglaznogo pressure decrease fields and the severity of, damage to the visual stimulus, cataracts, corneal perforation, the development of fungal infection.

Specific guidance

Can Apply while the drivers of vehicles and people skills relate to the high concentration of attention.

Precautions

If necessary, continue treatment over 2 weeks, a systematic monitoring vnutriglaznogo Davlenia.ne use in the event of a malfunction and bruised cornea (slow healing contribute to the spread of infection). Be wary of a host of diseases involving istoncheniem cornea (possible corneal perforation). When viral diseases caused by Herpes simplex, apply only in the combination therapy at the same time as противогерпетическим и means, and only under constant surveillance by an ophthalmologist.

Dosing and Administration

Locally. Eye drops on the 1-2 drops or eye ointment (mortgage for cat) 3-4 times a day. Perhaps a combination of : in the course of the day, eye drops, the night - ointment; Treated to 2 weeks.

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