Cortizone

Roman name

Cortisonum

Of drugs

For the application in medical practice produces acetate eye. Has impact on the protein and carbohydrate exchange. Decreases total protein in the plasma, mostly globulinovu faction, which is why альбуминоглобулиновы й The rising. Do the katabolizma (of the protein) in the muscles, at the same time contributes to the synthesis of products in the liver and kidneys, ie Braking is the synthesis of protein in some tissues and accelerates the formation of others. Controls process deamidization (fission) amino acids in the liver. Katabolicescoe and anabolicescoe (increasing), the eye of protein synthesis is realized through its impact on the nucleic acid. Kataboliceski preparation by the impoverishment of the body protein and muscle atrophy (decrease mass and the mus 1000 cle), osteoporosis (eating disorders bone accompanied by the increase in its friability) as a result of protein resorption of bone in excess glkjokortikoidov (cortex hormones napochechnikov affecting carbohydrate and protein exchange).

Storage conditions

List B. In the dark spot.

Indications for use

Arthritis, rheumatoid arthritis (инфекционно-аллергич еская disease from the kollagenozov characterized by chronic progressive inflammation of joints), and other kollagenozy (obshee a disease characterized by diffuse loss of connective tissue and vessels), bronchial asthma, acute myeloblastic and lymphoblastic leukaemia (malignant tumor blood emerged from the blood cells of bone marrow), infectious mononucleosis (severe viral infection, either with a high temperature rise of the body, increase nebnykh nodes, liver), neirodermit (diseases of the skin caused by the violation of the central nervous system), eczema (neiroallergicescoe skin disease characterized moknuschim, zudahim inflammation), and other skin e61 conditions Addison disease (low napochechnikov function), and severe crimes substance napochechnikov, haemolytic anaemia (increased erythrocyte breakdown), glomerulonefrit (kidney disease), viral hepatitis (inflammation of the liver tissue, caused by the virus), acute pancreatitis (inflammation of the pancreas), collapse (a sharp fall in blood pressure) and the shock of various nature (post, anaphylactic / allergic / cardiogenny etc.).

Dosing and Administration

Assign inwards or intramuscularly (in the form of suspension / suspended particulates drug in liquid /).

Side-Effects

Cortizone side than others глюкокортикостероидн ые drugs is a matter of side effects. Leaving the treatment and the use of high doses (more than 0.1 grams per day) may be obesity, girsutizm (excess owolosenie for women reflected growing beards, writing, etc.), acne, menstrual irregularities, osteoporosis, simptomokomplex Itsenko-kushinga (obesity, with corresponding declines sexual function improved and bone fractures as a result of the strengthened адренокортикотропног о pituitary hormone), personality disorders, etc. There izgyazwlenia digestive tract perforation nerspozn ff9 anna ulcer (a defect through the stomach wall or bowel thin on the ground ulcer), haemorrhagic pancreatitis (inflammation of the pancreas, proceeding with bleeding in her body). As a result of the emergence of a more efficient, better over synthetic drugs glukokortikoidnykh cortizone is now limited.

Contraindications

Essential hypertension hard time (solid recovery blood pressure), diabetes, a disease Itsenko-kushinga, pregnancy, circulatory insufficiency III stage disease hospital, recently transferred operation, syphilis, the active form of tuberculosis, aged age.

Form of

Answers to 0.025 and 0.05 g; Suspension in vials containing 10 ml (1 ml suspension contained 0,025 grams eye acetate).

Directory → Hormones and their antagonists → Adrenal → Glukokortikoida → Cortizone