Directory → Hormones and their antagonists → Adrenal → Glukokortikoida → Lokoid
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LokoidSee also HalometasoneRoman nameLocoidThe composition and the form of1 g ointment contains hydrocortisone 17-butirata 1 mg; in the box to 30 grams in a box one dose.PharmacokineticsFollowing application on the skin accumulate in the epidermis. Absorbirovannaya of metabolized directly to the epidermis, and then in the liver. Metabolites and a small portion unchanged hydrocortisone butirata presented with urine or jelchew and faeces.Clinical pharmacologyThe Lokoida comparable with many halogenated steroidami, and the risk of side effects when used significantly lower than those of halogenated steroids. When used in the recommended doses, it is the suppression of гипоталамо-гипофизар��о-адреналовой system.IndicationsEczema and dermatitis (surface neinfizirovanne), psoriasis and other diseases, which are sensitive to local therapy glukokortikoidami, in adults and children from 6 months.Pregnancy and lactationDuring breastfeeding large quantities Lokoida ® nominated with caution. When causing long body surface during pregnancy may impact on the fruit.ContraindicationsHypersensitivity, pink and vulgar acne, lokalizutesa the person okolorotova dermatitis, as well as dermatitis, bacterial cause (such as impetigo), infection (eg, simple herpes), fungi (eg candidiasis or dermatofitia) infections; Perianalny and genital itching, parasitic and skin infections (scabies), the wounds.Side-EffectsThe drug is generally well tolerated. There are local reactions : skin irritation, contact allergy.Patient interactionData on medication interaction Lokoida not.OverdosingData on overdose Lokoida not. With long-term use the drug in high doses may cause symptoms gipercortitizma.PrecautionsWith long-term use of large surfaces damaged skin or using occluzih casts increases the risk of local and systemic side effects, and it is recommended that monitor body weight (children), to monitor the level of cortisol plasma. In applications in the area of a person or occluzie bandages treatment in children back.Dosing and AdministrationExternal, a small quantity of toning movements caused by depressed skin 1-3 times a day. If a steady improvement can be used from every day to two or three times a week. In the case of resistance (in the localization psoriaticakih tight spots on the elbows areas knees), chaired occluzie dressing. Weekly dose should not exceed 30-60 grams in normal cases.Storage conditionsWith an ambient temperature of 15 to 25 ° C, in a well-ukuporenna packagingShelf life5 yearsThe registration013840/01-2002 |
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