Directory Hormones and their antagonists Adrenal Glukokortikoida Lokoid
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Lokoid

See also Halometasone

Roman name

Locoid

The composition and the form of

1 g ointment contains hydrocortisone 17-butirata 1 mg; in the box to 30 grams in a box one dose.

Pharmacokinetics

Following application on the skin accumulate in the epidermis. Absorbirovannaya of metabolized directly to the epidermis, and then in the liver. Metabolites and a small portion unchanged hydrocortisone butirata presented with urine or jelchew and faeces.

Clinical pharmacology

The Lokoida comparable with many halogenated steroidami, and the risk of side effects when used significantly lower than those of halogenated steroids. When used in the recommended doses, it is the suppression of гипоталамо-гипофизар��о-адреналовой system.

Indications

Eczema and dermatitis (surface neinfizirovanne), psoriasis and other diseases, which are sensitive to local therapy glukokortikoidami, in adults and children from 6 months.

Pregnancy and lactation

During breastfeeding large quantities Lokoida ® nominated with caution. When causing long body surface during pregnancy may impact on the fruit.

Contraindications

Hypersensitivity, pink and vulgar acne, lokalizutesa the person okolorotova dermatitis, as well as dermatitis, bacterial cause (such as impetigo), infection (eg, simple herpes), fungi (eg candidiasis or dermatofitia) infections; Perianalny and genital itching, parasitic and skin infections (scabies), the wounds.

Side-Effects

The drug is generally well tolerated. There are local reactions : skin irritation, contact allergy.

Patient interaction

Data on medication interaction Lokoida not.

Overdosing

Data on overdose Lokoida not. With long-term use the drug in high doses may cause symptoms gipercortitizma.

Precautions

With long-term use of large surfaces damaged skin or using occluzih casts increases the risk of local and systemic side effects, and it is recommended that monitor body weight (children), to monitor the level of cortisol plasma. In applications in the area of a person or occluzie bandages treatment in children back.

Dosing and Administration

External, a small quantity of toning movements caused by depressed skin 1-3 times a day. If a steady improvement can be used from every day to two or three times a week. In the case of resistance (in the localization psoriaticakih tight spots on the elbows areas knees), chaired occluzie dressing. Weekly dose should not exceed 30-60 grams in normal cases.

Storage conditions

With an ambient temperature of 15 to 25 ° C, in a well-ukuporenna packaging

Shelf life

5 years

The registration

013840/01-2002

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