Polcortolon 40

Roman name

Polcortolone 40

The composition and the form of

1 ml suspension for injection contains triamtinolona azetonida 40 mg and benzyl alcohol 9.9 mg in izotonicescom solution of sodium chloride; Dissolve in 1 ml, in a Box 5 bottles.

Of drugs

Induces education lipokortinov hampered fosfolipazu A_2, oppressing release eozinofilami mediators inflammation, reduces the number of fat cells, generating gialuronovu acid and hampers their degranulation. Impact capillary permeability, stabilizes cell, including lizosomaiona membranes. Lock up Cytokines (interleikina 1, 2, gamma-interferon) from the cells and macrophages. Increases glukoneogenez lowering glucose disposal tissues and activates katabolicescie processes.

Indications

Sennaya fever, bronchial asthma, chronic bronchitis spasticeski. Vnutrisustavno : chronic inflammatory diseases of the joints, ekssoudativei arthritis, gout, false gout, arthritis, hydrocysts joints, and the blockade of shoulder pain, chronic inflammation of internal layer joint capsules; Injections under the infested area : isolated psoriaticalkie times, flat uzelkove destruction, loss of hair in the form of a circle chronic red erythematosus, kelloida.

Pregnancy and lactation

Not recommended.

Contraindications

Hypersensitivity open tuberculosis, diabetes, malignancies, hepatitis, gastric ulcer and duodenal ulcer, bone defects, mental illness (including in history), viral infections (vesicular disease herpes, herpes zoster), chickenpox, and amebnye fungal infection, poliomyelitis (with the exception of бульбарно-энцефалитн��й forms), glaucoma, children's age (up to 6 years).

Side-Effects

When s / to the introduction-obratimaya bone tissue; Russia intra-necrosis of bone, a sense of heat; A wide-lunoobraznoe person syndrome Kushinga, napochechnikov atrophy, muscle weakness, atrophy of bone and muscle, diabetes mellitus, the pain, impotence, increased hair growth, bleeding from the skin and mucous membranes, skin, gipokaliemia, vasculita, ulzerogennoe act immunosuppression, headaches, increased sweating, glaucoma, thrombosis, the syndrome.

Patient interaction

Do effect of oral anticoagulants. Impact - protivodiabeticakih funds. Increases toxicity of cardiac glycosides (in a gipokaliemii) and ulzerogennosti salicilatov. Activity reduce barbiturates glimid (noxiron) противоэпилептически е and antipruritic drugs. Anabolic steroids increase the risk of swelling.

Precautions

There is a need to be careful when stomach ulcers and duodenal ulcer (in history), divertikulitah, fresh anastomozah bowel, and the inclination to trombozam, emboliam, kartsinomah the tendency towards metastezirovaniu, glomerulonefrite acute, chronic nephrite. If infection there should be vnutrisustavno in / in and s / GMT

Dosing and Administration

V / m. Adults for systemic treatment-1-2 ml (40-80 mg) being slowly deep in the gluteus muscle (re-introduction of the 4 th); Vnutriochagovom the application (bursitis) adults and children over 12 years of age, from 10 to 40 mg. The interval between injections at least two weeks. For the area under the skin lesions 1 ml of diluted local anestetikom and enter 1 mg preparation of 1 cm ^ 2 (no more than 30 mg per day for adults and 10 mg / day for children). Re-injection two weeks.

Storage conditions

List B. In a dry, the dark spot

Shelf life

3 years

The registration

010,546 (Ann.2003)

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