Directory Hormones and their antagonists Adrenal Glukokortikoida Prednisolone injection
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Prednisolone injection

See also Mazipredone

Roman name

Prednisolon for injections

The composition and the form of

1 ml solution for injection contains mazipredona hydrochloride 30 mg; USD in 1 ml, in a box three ampoules.

Characteristics

Washable synthetic derivative PREDNISOLONE.

Of drugs

Protivosokowoe, protiwallergicescoe, противовоспалительно е. Like other glukokortikoida increases peptide fusion inhibitors fosfolipaza A_2, reduces the GHG reduces the macrophagic hemotaksicski factor inhibits migration of macrophages and lymphocytes in the center of inflammation, stabilize membranes lizosom (preventing the lysosomal enzymes), from the release of sensitised fat cells and bazofilov gistamina and other biologically active substances.

Indications

The shock, severe allergic reactions, asthma status severe napochechnikov, hepatic coma.

Pregnancy and lactation

Contraindicated during pregnancy; Through breastfeeding should stop breast-feeding in the event of a child giperbilirubinemii.

Contraindications

In applying for health reasons no contraindications. Leaving the treatment : hospital disease stomach and duodenal ulcers, Kushinga syndrome, osteoporosis, psychosis.

Side-Effects

Azwoobrazovanie in blood, giperglikemia, diabetes mellitus, arterial hypertension, osteoporosis, gipokaliemia insufficient functions crust napochechnikov, nitrogenous negative balance reduced resistance to infection; Local reactions : passing pain infiltrata in place in the / m application.

Patient interaction

Barbiturates, speeding metabolism, the effect of weakening. Reduces effective oral gipoglikemisiruth products increases gipokaliemia against dioretikov increases the risk of gastrointestinal bleeding in the admission NPVS and anticoagulants.

Dosing and Administration

In / in or / m in shock-150 mg, on the other eyewitness accounts, 45 mg; Children 2-12 months, 2-3 mg / kg, 1-14 years, 1-2 mg / kg

Storage conditions

r-r d / in. : List B. At temperatures below 15 ° C

Shelf life

r-r d / in. : 2 grams.

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