Solu-medrol

Roman name

Solu-Medrol

Of drugs

Глюкокортикостероидн ое

Storage conditions

List B. In a cool, the dark spot.

Shelf life

5 years. The solution is suitable for use within 48 hours of preparation.

The registration

008,375 (Ann.2003)

Indications for use

Endocrine diseases such as primary or secondary napochechnikovaya deficiency, congenital giperplazia (expansion) napochechnikov, negnany tireoidit (negnanoe inflammation of the thyroid gland), giperkalyshsmia (high concentrations of calcium in the blood) as a result of tumor diseases. Rheumatic diseases short course as an adjuvant therapy, as the process. Воспалительнодегенер ативные and metabolic bone disease, including psoriaticeski arthritis (joint inflammation in psoriasis), rswmatoidnyi arthritis ( инфекционно-аллергич��ская disease from the kollagenozov characterized by chronic progressive inflammation of joints), uvenilny (in childhood or adolescence), rheumatoid arthritis, ancylosing spondylitis (spinal disease), acute and podostry bursitis (inflammation of bone bags), and acute Baby tendoshinovit (socetannoe inflammation of the tendon, and the inner lining of joints) acute gouty arthritis (joint inflammation as a result of accumulation in the tissues of joint uric acid), traumatic osteoarthritis (nevospalitelnoe joint disease), sinovit (inflammation of the inner lining of joints), with osteoartroze, epikondilit (inflammation of a limited portion of the humerus bone, the seat attachment of muscles and tendons).

Dosing and Administration

As an adjuvant therapy for life-threatening conditions that dose of 30 mg / kg body weight. The agent introduced intravenously for at least 30 minutes. Introduction can be repeated every four to six hours

Side-Effects

Violations menstrual cycle, the development of Kushinga syndrome (obesity and the resulting decline in sexual function, increased bone fractures as a result of the strengthened адренокортикотропног о pituitary hormone), the suppression of �ипофизарнонадпочечн��ковой axle (suppression of pituitary hormones regulating function napochechnikov), a decline of tolerance (Time) to carbohydrates, demonstration diabetes mellitus (raising blood sugar in patients with subtle forms of diabetes), increased need for insulin or oral (of the mouth) gipoglikemisiruushih (negative blood sugar) of the patients, growth suppression in children. Steroidnaya miopatia (muscle weakness due to a violation of steroid hormones), osteoporosis (eating disorders bone accompanied by the increase in its friability), pathological fractures, compression (caused by compression) vertebrae fractures, aseptic necrosis (tissue eliminate) joints. Pepticalkie ulcer (stomach ulcers, colon or esophagus, as it has evolved as a result of the destructive actions of gastric juice in the mucous membrane), with the possibility of perforation (a defect through the wall), and bleeding, jeluderne hemorrhage, pancreatitis (inflammation of the pancreas), ezofagit (inflammation of the oesophagus), perforation of the bowel. Violations of healing, petehii (point bleeding under the skin or mucous membranes) and ekhimozy (extensive bleeding into the skin or mucous membranes), and thinning of the fragility of the skin. The vnutricerepnogo pressure, personality disorders, depression (are men), extreme mood apnoea seizures, back subkapsuliarnaya cataract (eye disease, characterized by partial or total decreased aphykia eye localizations fire under aphykia capsule), the vnutriglaznogo pressure exofthalm (shift eyeball patterns forward, accompanied by the expansion of eye slits, secondary eye infection caused by viruses and fungi. Erase clinical picture of infectious diseases, more latent (hidden) infections, the suppression reaction to the allergens in the skin samples, increased susceptibility to fungal, viral and bacterial infections. Delay sodium, potassium loss, gipokaliemicski alkaloz (zachelachivanie blood, accompanied by the lowering of potassium ions), increased excretion (a), calcium delay liquid. The negative balance of nitrogenous the metabolism (decomposition) proteins. Allergic reactions, cardiac arrest, bronhospazm (sharp narrowing of the bronchi clearance), the disruptions to the heart, arterial hypertension (raising blood pressure) or hypotension (low blood pressure).

Contraindications

Systemic fungal infections; Hypersensitivity to metilprednizolonu.

Form of

Sterilized powder for intramuscular and intravenous use in vials of 0.02 g, 0.04 g, 0,125 g, 0.25 g, 0.5 g, 1.0 g or 2.0 g metilprednizolona sodium succinate together with the solvent.

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