Directory → Hormones and their antagonists → Adrenal → Mineralokortikoida → Florinef
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FlorinefSee also FludrocortisoneRoman nameFlorinefThe composition and the form of1 tablet contains fludrokortizona acetate 0.1 mg; in vials of 100 pcs.Of drugsGlukokortikoidne. Fills deficit hormones napochechnikov crust. Participates in metabolism, including mineral and uglevonom; is the delay of sodium ions and contributes to the development of potassium.Заместительная терапия при выраженной недостаточности коры надпочечников, в частности, при болезни Аддисона, адреногенитальный синдром с потерей солей.Substitution therapy with insufficient expressed napochechnikov crust, in particular with Addison disease, adrenoguenitalny syndrome loss of salts.Pregnancy and lactationDuring pregnancy (especially in the first trimester) will be appointed only on the absolute condition. Lactoirutm women should give up breast-feeding.ContraindicationsMental disease, herpetic viral infection amebiaz, systemic mikozy, saying disease stomach and duodenal ulcers, polio, osteoporosis, both before and after immunization.Side-EffectsUsing high doses of oppression glands (glands lectures ACTG), a decline in the thymus and education cortisol, glukoneogeneza policy, a negative balance of nitrogenous, oppression growth in children, subkapsuliarnae cataracts, the vnutriglaznogo pressure petehii, erosivno-azwenne shock syndrome, menstrual irregularities, oedema, the AD asepticalkie bone necrosis.PrecautionsBe wary appointed to ulcers in history, gravis, divertikulitah recently completed anastomozah bowel, and the inclination to trombozam and emboliam, metasteziruta carcinoma, tuberculosis (possible activation process), diabetes (likely decompensation). To avoid eye and AD patients is recommended that the diet restricted consumption of table salt. If there is infection in the face of drug treatment to the immediate appointment of antibiotics or himiopreparatov. In long-term care should regularly monitor the concentration of electrolytes and glucose in the blood serum.Dosing and AdministrationInside, from 0.1 mg three times a week, up to 0.2 mg per day. Patients with arterial hypertension, to 0.05 mg per day. The award, coupled with kortizonom (6,25-25 mg per day) or gidrokortizonom (5-20 mg / day), especially in substitution therapy.Storage conditionstable. : List B. |
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