Batriden

Chemical name

1,1',6,6',7,7'-Гексаокси-3,3'-��иметил,-5,5'-диизопропи л-8,8'-диформил- 2 ,2'-динафтилидендибарб итуровая acid

Gross

C38-H34-N4-O12

Characteristics

Amorphous powder from Kim to dark colors. Gigroskopichen. Virtually nerastvorim in water and ethanol.

Of drugs

The drugs-immunodepressivne. Provides limfozitotoksicescoe effect. With long-term use increases the survival allotransplantatov kidney.

Indications

Preventing transplant rejection (after kidney allotransplantation) combined with korticosteroidami and local X-ray exposure (on the grounds).

Pregnancy and lactation

Contraindicated in pregnancy.

Contraindications

Hypersensitivity, and infectious diseases uses, the presence of the hidden sources of infection, pregnancy.

Side-Effects

Infectious complications (in the employment of large doses) : postoperative festering wounds of bronchopulmonary infections, infections of the urinary tract.

Patient interaction

Compatible with korticosteroidami. Potenziruet the gipotenziveh funds. It should not be combined with azatioprinom, ziklofosfamidom, metotrexatom, etc.) in order to avoid the increased side effects.

Precautions

Control AD : on the first day, 3-4 times, in the future, every day. To prevent septic complications can use broad-spectrum antibiotics. In the case of secondary infection dose batridena reduce, control of the allotransplantata.

Dosing and Administration

Inside (regardless of meals), the dose of 1.5-6 mg / kg / day in 2-3 reception. Dose dependent on the number of cells in the peripheral blood. Therapy continues throughout the life of the patient with transplantatom.

Directory → Immunotropona funds → Immunosuppressants → Batriden