Ciclosporin

Roman name

Cyclosporinum

Of drugs

The drug has a powerful immunodepressivna activity (suppresses the immune system), prolongs the survival time of allogeneic transplants (tissue or organs for transplant from the donor / other rights) : the skin, kidneys, heart, etc.

Storage conditions

obr.stand.-por. : List B.

Indications for use

Ciclosporin is the principal means of preventing exclusion transplantanta with allogeneic transplants (renal tissues or organs from the donor) kidneys, the heart, lungs and other organs, as well as in the b 6d10 one marrow.

Dosing and Administration

The drug is injected and inwards. The transplants are treated for 12 hours before transplantation operation (transplant). When bone marrow starting dose before entering operation.

Side-Effects

In applying to the preparation of the kidneys and liver, hypertension (persistent rise in blood pressure), gipsrtrihoz (Muslim expansion hair or proper sex and age), Denmark (expansion) gums, tremor (shaking limbs), parestesia (feeling numbness in the extremities), loss of appetite, nausea, vomiting, diarrhea, giperkaliemia (increase of potassium in the blood), increasing the concentration of uric acid in plasma, dismenorea (the menstrual cycle), amenorea (lack of menstruation), muscle cramps, convulsions, mild anaemia (decrease in hemoglobin in the blood), increased sensitivity to infection, the development of malignant and limfoproliferativeh diseases.

Form of

Solution reception inside containing 100 mg in 1 ml; Concentrate intravenous infusions (ml to 1 or 5 ml containing 50 or 650 mg in 1 ml); Capsules containing 50 or 100 mg of cyclosporine. Solution cyclosporine comes with the полиоксиэтилированно го castor oil (which can sometimes cause anaphylactoidnye reaction / allergic reactions immediate type), and ethanol.

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