Sandimmun-neoral

Roman name

Sandimmun -Neoral # #

The composition and the form of

1 jelatinova soft capsule contains cyclosporine 25, 50 or 100 mg; in the package 50 and 100 st.1 ml for admission into 100 mg; in vials of 50 ml mle.1 concentrate preparation infuzing solution-50 mg; USD in 1 and 5 ml, in a package 10 pcs.

Of drugs

Immunodepressivne. Does the cell cycle clock cells in phases G_0 or G_1 and suppresses zapuskaemuyu Antigen products and secretion limfokinov (including interleykin-2-growth cells) T-limfozitami activated.

Farmakodinamika

Imagine the reaction of cell types, including resentment allotransplantata illness "transplant to the owner, skin гиперчувствительност ь slow type allergic encephalomyelitis, arthritis due to adjuvant Franda, dependent on education cell antibodies.

Indications

The transplantation of solid organs (kidney, liver, heart, serdern-legochny set, lungs, pancreases), and bone marrow; Endogenous uweita, principally syndrome expressed forms of rheumatoid arthritis in the active phase, severe psoriasis and atopic dermatitis.

Pregnancy and lactation

During pregnancy used with caution. Breast-feeding at the time of treatment should be discontinued.

Contraindications

Гиперчувствительност ь.

Side-Effects

Pain in the abdomen, anorexia, nausea, vomiting, diarrhoea, headache, weakness, parestesia, convulsions, muscle cramp, miopatia, tremor, hypertension, the effects on the kidneys and liver, swelling, pancreatitis, obratimaya dismenorea and amenorea, anaemia; B19, in some cases accompanied by mikroangiopaticescoy hemolytic anemia and renal insufficiency; Giperkaliemia, giperuriquemia, gipomagniemia, increased body mass index, Denmark gums, gipertrihoz, increased susceptibility to infection, the development of neoplastic and limfoproliferativeh disorders.

Patient interaction

Reduces the vaccination.

Precautions

The treatment is carried out only in specialized hospitals under systematic monitoring AD, the kidney and liver, the concentration of potassium in the plasma level of lipids in the cell, etc. should be avoided excess of potassium in the body (with food in kalisoderjasimi drugs), it is not advisable to appoint kalisberegate dioretiki. Be wary appointed to the human liver / kidney gieperriquemii, giperkaliemii.

Dosing and Administration

The initial dose and adjust the dosage in the treatment of a given clinical and laboratory parameters, as well as the concentration of the drug in plasma determined daily. Capsule should swallow whole.

Storage conditions

kaps.jelatin. : List Bo.r-r reception inside : List Bo.r-r reception inside : List B. The temperature is not above 30 ° C

Shelf life

r-r reception inside : 3 g.

Directory → Immunotropona funds → Immunosuppressants → Sandimmun-neoral