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GepatectSee also Immunoglobulin human hepatitis bRoman nameHepatect #The composition and the form of1 ml for infusions of antibodies against hepatitis B 50 IU 100 mg plasma proteins (of which Ig> = 95%); in the sealed-2, or 10 ml, in a cardboard bundle 1 USD.CharacteristicsColorless or white light or slightly opalestiruty solution.Of drugsImmunomodulirutee.IndicationsEmergency prevention of hepatitis B after contact with the infected material (blood, plasma, serum), the prevention of HIV liver transplant from Hbsag-polaugitionah patients, the prevention of hepatitis B in newborns whose mothers are HIV surface antigen hepatitis B, the people are great (to the operation of re gemotransfuziei, haemodialysis, etc.) or constant risk of infection, including unable to develop enough protective antibodies.Pregnancy and lactationWith caution.ContraindicationsHypersensitivity, Carrier surface antigen of hepatitis B.Side-EffectsHeadache, fever, increased body temperature, nausea, vomiting, lomota in joints, pain in the back, allergic reactions. Seldom-reduction actions, in a few cases, anaphylactic shock, the symptoms of aseptic meningitis (severe headache, nausea, vomiting, increased body temperature, rigidity cervical muscles SHP, a violation of consciousness), the worsening renal failure in patients with compromised renal function.Specific guidanceYou can only mix with izotoniceski solution of sodium Hlorida.vozmozhno a lozhnopolaugitionah data serologicescom study.Patient interactionImpact on the living virus vaccines (measles, rubella, mumps and chicken pox).Dosing and AdministrationIn / in slowly, with a> = 40 ml, with a speed of no more than 20 drops / min (1 ml / min) (ampoules previously heated to room temperature and the temperature of the body). Emergency prevention : 6-12 IU / kg, but not less than 10 Ml.prophylactika at high risk of infection : 7 IU / kg, but not less than 10 ml, every 2 months (in the absence of antibody to HBs after one month) until Antitel.prophylactika HIV liver transplant : the removal of the liver to transplant 10,000 IU (200 ml) after the operation-2000 IU (40 ml) daily for 7 days, and further that, in accordance with the results of a monthly monitoring (content in the serum of not less than 100 IU / l). Prevention of hepatitis B in newborns : one 20 IU / kg, but not less than 2 ml.Storage conditionsr-r d / inf. : In the dark place at a temperature of 2-8 ° C (not freezing)Shelf lifer-r d / inf. : 2 grams. |
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