E.g. VIENA n.i.v.

Roman name

IG VENA N.I.V.

The composition and the form of

1 antiseptic solution for the on / in infusions together with sterile apirogennam device for the solution of the normal human immunoglobulin polivalentny double viral inactivation 1, 2.5, 5 and 10 g; Patients in the 20, 50, 100 and 200 ml, respectively. 1 ml of 50 mg of active substance.

Characteristics

Structurally and functionally complete Ig molecule with all the properties of antibodies; The ratio of IgG subclasses (IgG1, IgG2, IgG3, IgG4) is similar to natural; Is the lack of low IgA.

Of drugs

Immunomodulirutee, immunostimulating. And IgG activity increases (doniruet) antibody against various infectious agents. Improves supressornuyu activity blocks Fc receptors (for a part Ig) for macrofagah regulates cell activity, reduces the number of IgG and complement level.

Indications

Substitution therapy with the deficiency (primary, secondary, combined, variabelny) : congenital agammaglobulinemia, illness Bruton, gipogammaglobulinemia, Vizcotta syndrome, Aldric, HIV, chronic limfoproliferativee disease, multiple mieloma, organ transplantation; Immunomodulirutaya therapy : Kawasaki syndrome, idiopathic thrombocytopenia Autoimmune, Giyena syndrome - Barre polineiropatia, infants, multiple sclerosis, epilepsy refrakternaya for children antifosfolipidnyi syndrome accompanied by spontaneous miscarriage, systemic lupus red and other infections in newborn and premature babies (prevention and treatment).

Pregnancy and lactation

With caution.

Contraindications

Intolerance donor immunoglobulin, incl. with IgA deficiency due to the presence of the antibodies.

Side-Effects

From the nervous system and sensory organs : rarely headache Bol.so the circulatory system and blood (blood, gemostaz) : rarely drop Ad.so the respiratory system : rarely shivers, Lichoradka.so part of the intestine : rarely vomiting, Toshnota.prochie : artralgia, pain in the back, allergic reactions, anaphylactic shock.

Specific guidance

Not to be confused with a sprite with other drugs. In / in the introduction leads to a transitory increase antibodies, which may lead to a lozhnopolojitelny serological studies.

Patient interaction

Ters the live vaccines against measles, rubella, mumps, chicken pox for a period of six weeks to three months.

Dosing and Administration

B / drip in the (pre-heated to room temperature or body temperature), with a speed of 10 to 20 drops per minute for 20-30 minutes, then the speed can be gradually increased to 40 drops in минуту.Заместительна�� therapy in primary and secondary immunodefitsitah : 100-400 mg (2-8 ml) / kg once per month, with a lack of dose increase to 800 mg (16 ml) / kg or Frequency �ведения.Трансплантац ия bodies with immunosuppression : before and after transplantation, the initial dose of 500 mg (10 ml) / kg / week supporting-500 �г/кг/мес.Иммуномодули рующая Therapy : 400 mg (8 ml) / kg daily for five days, or 1000 mg (20 ml) / kg for 2 days, if necessary, to re-six courses.

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