Intraglobin

Roman name

Intraglobin #

The composition and the form of

1 ml for on / in the introduction of plasma proteins rights 50 mg (including Ig> = 95%); 182,000,000 in the 10 or 20 ml bottle in 50 or 100 ml, in a cardboard bundle one peeling or 1 bottle.

Characteristics

Colorless or white light or slightly opalestiruty solution.

Of drugs

Immunomodulirutee.

Indications

Congenital deficiency (full-selective VARiational heavy combined), or selective gained, with emergent bacterial infections (in patients with chronic leukaemia limfocitarian, mieloma); Recurrent bacterial infections in children with AIDS; Immunomodulyatsia with idiopathic trombozitopenicescoy purpure (especially acute in children), allogeneic bone-marrow transplants, Kawasaki syndrome.

Pregnancy and lactation

With caution.

Contraindications

Гиперчувствительност ь.

Side-Effects

Headache, fever, increased body temperature, nausea, vomiting, lomota in joints, pain in the back, allergic reactions. Seldom-reduction actions, in a few cases, anaphylactic shock, the symptoms of aseptic meningitis (severe headache, nausea, vomiting, increased body temperature, rigidity cervical muscles SHP, a violation of consciousness), the worsening renal failure in patients with compromised renal function.

Specific guidance

You can only mix with izotoniceski solution of sodium Hlorida.vozmozhno a lozhnopolaugitionah data serologicescom study.

Patient interaction

Ters the living virus vaccines (measles, rubella, mumps, chicken pox).

Overdosing

Symptoms : gipervolemia, high viscosity of blood (especially in patients with impaired kidney or in old age).

Precautions

Do not exceed the recommended rate of application (probably the heavy side effects). Throughout the infusions and within 20 minutes after the patient must be under medical supervision.

Dosing and Administration

In / in in the form of infusions or injections (before the solution was heated to room temperature or body temperature); Initial speed Infusion 30 drops / min, maximum 40 капель/мин.Заместител ьная therapy in the primary or secondary immune : 2-8 ml / kg at intervals of 1 month; unless there is an adequate level of IgG, or a rapid drop dose can be increased up to 16 ml / kg or reduce interval �ведениями.Идиопатиче ская trombozitopenica purpura : at the beginning of 16-20 ml / kg (with the need to repeat on the second and third day), or 8 ml / kg / day within 2-5 Dnei.allogennaya bone marrow transplantation : before and after transplantation in the dose of 10 ml / kg / Ned.sindrom Kawasaki : 32-40 ml / kg in a number of techniques for 2-5 days or by 40 ml / kg, in addition to medication acetylsalicylic acid.

Storage conditions

r-r d / inf. : In the dark place at a temperature of 2-8 ° C (not freezing) r-r d / in. : In the dark place at a temperature of 2-8 ° C (not freezing)

Shelf life

r-r d / inf. : 2 gu.r-r d / in. : 2 grams.

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