Interleukin-2 recombinant human

Characteristics

Rekombinantny interleykin-2, a biotech methods of kletok-produzenta - recombinant strain nepatogennah bakery yeast Saccharomyces cerevisiae, in the genetic apparatus which built interleikina gene, 2. It is a polypeptide consisting of 133 amino acids, is a structural and functional analogue of the human endogenous интерлейкина-2.Лиофил��зированный powder or porous mass of white or white with a yellowish sheen color. Gigroskopichen easily soluble in izotonicescom solution of sodium chloride.

Of drugs

The drugs-immunomodulirutee. Associated with specific receptors on the "kletkah-misheniah, stimulates growth and differentiation of T proliferatiou and V-limfozitov, monocytes, macrophages, oligodendroglialnah cells Langergansa cells. It is a matter of education лимфокин-активирован��ых blood, activates �пухоль-инфильтрирующ ие cells. Does zitoliticescuu activity of natural killers and cytotoxic lymphocytes. Enhance the immune response (antibacterial, protivovirusny, protivogribkovi, противоопухолевый).Эф фективен in the integrated therapy �нойно-воспалительных �infectious diseases (peritonitis, pancreatitis, osteomielit, abscesses and flegmona, tuberculosis, hepatitis C, yersiniosis, chlamydia, mikozy etc.), in immunohimioterapii (melanoma, colorectal cancer, etc.), for the prevention of secondary immunodeficiency syndrome (post, in the face of radiation, chemotherapy and hormone therapy).

Indications

Septic condition associated immunosuppression (sepsis trauma, surgery, akushersko-ginekologicaki, Burns, Wound etc.), as part of an integrated therapy; Malignant neoplasms, including kidney cancer.

Pregnancy and lactation

Contraindicated in pregnancy.

Contraindications

Hypersensitivity, incl. against yeasts, auto and heavy cardiovascular disease, pregnancy.

Side-Effects

Grippopodobnyy syndrome (acute vomiting, increased body temperature).

Patient interaction

Compatible with other drugs.

Precautions

Quick in / in the introduction may be accompanied by the development of heart failure.

Dosing and Administration

B / drip in, and at speeds of 1-2 ml / min (within 4-6 h), s / c, vnutripolostno, Local. In sepsise, infectious and гнойно-воспалительны�� Diseases : 1-3 in the 0.5-1 mg intermittently 1-3 days. In kidney cancer and other malignant tumors : 0.5 mg 24 hours before the operation, after nefrektomii to stage III cancer, 2 May Day introductions to 1 mg a day, with the IV-10 varieties to 3 mg a day. Repeated courses are conducted in 1-2 months.

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