Leacadin

Chemical name

2-carbamoilaziridin

Gross

C3-H6-N2-O

Characteristics

White melkochristalliceski powder. Easily soluble in water, sparingly soluble in ethanol, practically nerastvorim in chloroform and ether.

Of drugs

The drugs-immunomodulirutee, protivoopujolevoe, противопсориатическо е. And immunomoduliruta activity manifested mainly in people with compromised immunity (decrease in the total number of immunocompetent cells, the ratio of Т-хелперы/Т-супрессор��). Reduces the supressornah cells, the ratio normalizes T-helpera/t-supressora enhances cytotoxicity kletok-killerov and monocytes, slowing growth Opouholei.pri ingestion rapidly absorbed from the digestive tract. It permeates through gistogematicalkie barriers, including GEB through.

Indications

The immune to the combination anticancer therapy in adults (Kaposi sarcoma, etc.); In dermatology, including in psoriaticescoy eritrodermii, psoriaticescom arthritis, eritematose.

Contraindications

Hypersensitivity, lakopenia (less than 3x10 ^ 9 / L), thrombocytopenia (less than 12h10 ^ 9 / l), saying the disease stomach and duodenal ulcers, hypertension II stage throm (in the phase of deterioration).

Side-Effects

Nausea, vomiting, lakopenia, thrombocytopenia, the AD allergic reaction (urticaria, skin).

Precautions

When side effects should be reduced dose or cancel product.

Dosing and Administration

Inside, after delivery, 0.1 grams twice a day for 10-15 days. If necessary, repeat courses with an interval of 3 Ned.v / in, adults, in the 100-300 mg / m ^ 2 daily for 10-15 days.

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