Pirogenal

Roman name

Pyrogenalum

The composition and the form of

Lipopolisaharida S.typhi

Of drugs

The preparation has pirogennoe Effects (raises body temperature). Drug activity determined by biological and raise MPD (minimum pirogennaya dose). MPD one is the number of substances vzwatee through intravenous krolikam increase body temperature by 0.6 ° C and above.

Storage conditions

The potted sealed in the dark place at a temperature between 2 and 10 ° C.

Shelf life

supp.rekt. : 1.5 g.

Indications for use

Pirogenal applied to promote recovery after injury and diseases of the central and peripheral nervous systems; Resorption for pathological scars, adhesions after burns injuries, and spaernm process in the abdominal cavity in the treatment of patients suffering from infectious diseases, especially when they are prolonged, retidiviruuschem reaches (re-signs of the disease).

Dosing and Administration

Misleading intramuscularly once a day. Injections produce in a day or at long intervals (2-3 days). Doses to select individually. Initial dose is 25-50 MPD. Set dose causing the body temperature to 37,5-38 ° C, and give it to the rise in temperature, after which the dose gradually increased to 25-50 MPD. The maximum single dose for adults-1000 MPD. The course of treatment consists of 10 to 30 injections; Neobhoimosti to repeat it. Break between courses must be at least 2-3 months.

Side-Effects

In pirogenala overdose of individual patients may have chills, increased body temperature, headache, vomiting, pain in the lower back. These reactions are continuing normally 6-8 hours, after which the body temperature drops and the side effects disappear. In these cases, reduce the dose.

Contraindications

The drug can be sick with severe feverish (causing a sharp rise of body temperature) diseases and pregnant.

Form of

In sealed with a 1 ml izotoniceski solution of sodium chloride 100, 250, 500 or 1000 MPD.

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