Ronkoleikin

Roman name

Roncoleukinum #

The composition and the form of

1 USD with liofilizirovannam powder preparation infuzing solution containing recombinant interleikina-2 0.25, 0.5 or 1 mg (250,000, 500,000 or 1 million IU respectively); in a cardboard bundle five vials (complete with a knife ampulnam).

Characteristics

Structural and functional analogue of the endogenous human interleikina-2.

Of drugs

Immunomodulirutee. Fills deficit endogenous interleikina-2 and reproduces its effects. Working with the receptors, induces growth, differentiation and proliferatiou air and V-limfozitov, monocytes, macrophages, oligodendroglialnah cells epidermalnah Langergansa cells. It is a matter of education лимфокинактивированн ых blood, activates �пухоль-инфильтрирующ ие cells. Does zitoliticescuu activity of natural killers and cytotoxic lymphocytes increases the resistance of cells to programmed cell death-apoptozu. Provides immune protection : antibakterialnuyu, protivovirusnuu and protivogribkovu, protivoopujolevu.

Indications

Septic condition associated immunosuppression (sepsis trauma, surgery, akushersko-ginekologicaki, Burns, Wound etc.), malignant neoplasms, including kidney cancer.

Pregnancy and lactation

Contraindicated in pregnancy.

Contraindications

Гиперчувствительност ь to any component of the drug, allergy against yeasts, auto and heavy cardiovascular disease, pregnancy.

Side-Effects

Grippopodobnyy syndrome (short runs, hyperthermia).

Specific guidance

The homemade solution content capsules slowly dissolve in 1.5-2 ml sodium chloride injection and received solution carrying 400 ml izotoniceski solution of sodium chloride. To prevent the loss of biological activity of sodium, depending on the starting dose injection (1 mg, 0.5 mg or 0.25 mg) added 10% solution of whey human albumin (8, 6 or 4 ml respectively). During preparations solution should avoid flushing.

Precautions

Treatment is carried out under medical supervision.

Dosing and Administration

In / in, drip at the rate of approximately 1-2 ml / min (within 4-6 h), s / c, vnutripolostno, Mestno.pri sepsise, infectious and гнойно-воспалительны�� Diseases : 1-3 in the 0.5-1 mg intermittently 1-3 Dna.pri kidney cancer and other malignant tumors : 1 mg three times a week to / drip in the 1st and 4th week and 0.5 mg three times a week to / drip in the second and third weeks of treatment.

Storage conditions

por.liof.d / inf. : List B. In the dark place at a temperature of -4 to -20 ° C

Shelf life

por.liof.d / inf. : 2 grams.

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