Diffumal 24

Roman name

Diffumal # 24

The composition and the form of

delimaya one tablet contains theofillina 100 or 200 mg; blistere in 10 pcs. , in box 3 blisters.

Of drugs

Bronhodilatirtee, dioreticescoe. Ingibiruet fosfodiesterzu increases in the tissues Zamf reduces the airway smooth muscle. Increase bronchi vessels, mainly the brain, skin and kidneys. Decreases lung vascular resistance, eases pressure in a small range of diseases. Increase peripheral blood increases renal blood and the moderate dioreticski effect. Ingibiruet agregatia platelets, stimulates breathing center, the frequency increases and the strength of cardiac contractions.

Pharmacokinetics

Rapidly absorbed. The therapeutic effect was in the concentration in the blood of 10 to 20 µ g / J The volume of 0.5 l / mm 8% return, unedited, with the urine, the remainder is metabolized to 1,3-demetilmocheva acid and metilksantina (running through the kidneys). The therapeutic effect was in the concentration in the blood of 10 to 20 µ g / J

Indications

Bronchial asthma, bronchoobstructive syndrome with chronic lung diseases.

Pregnancy and lactation

During pregnancy for health reasons. Lactoirute women at the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, the acute myocardial infarction, gipotenzia.

Side-Effects

Diarrhoeal disorders, headache, insomnia, tachycardia, arrythmia, albuminurija, giperglikemia.

Patient interaction

Is not compatible with other xantina derivatives. Do (mutually) dioreticeski Furosemida effect. Simultaneous with the appointment rezerpinom can provoke tachycardia. Erythromycin, linkomicin, clindamycin and zimetidin increase concentration in the blood, nicotine (smoking) diminishes.

Overdosing

There is a need to determine the number of drug and the length of time that had elapsed since the reception, cause vomiting, stomach wash, to activated carbon. It should monitor the activities of the heart, the AD breath elektrolitny balance. When convulsing appoint benzodiazepines.

Precautions

Be wary designate children, people older gipertonickam, patients gipertireozom, diseases of heart, liver and kidneys, in hypoxia, patients with pulmonary heart disease, congestive circulatory insufficiency, pepticescoy ulcer. In combination with ephedrine or other bronhodilatirutmi simpatomimetikami be closely monitored. Chronic smokers patients are typically required a dose theofillina (decreasing concentration in the blood, reduced T_1/2).

Dosing and Administration

Inside, every day Utrom.detam weighing between 15 and 20 kg-200 to 300 mg (maximum); 20 to 25 kg, 400 mg (maximum); More than 25 kg-2 table. 200 mg (500 mg / day). Adults - 2 table. 350 mg (but not more than 2.5 Table). .

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