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Lozartan potassium

See also Losartan

Roman name

Losartan potassium

Of drugs

Specific receptor antagonist angiotenzina II (type ATi). He suppresses kinazu -ferment II, which destroys bradikinin. Reduces the total force on resistance vessels (resistance receptacles used blood), reduces postnagruzku (blood pressure in aorte by reducing peripheral vascular resistance current blood), reduces blood pressure. Reduces pressure in a small (pneumonia), the terms of circulation. It is natriyureticeski (away sodium ions in urine) and mochegonny effects reduces the concentration of aldosterone and norarenalina in blood. Maximum gipotenzivny (reducing blood pressure) develops effect through 3-6 weeks.

Storage conditions

subst.-por. : The temperature 15-30 ° C

Shelf life

subst.-por. : 4 g.

Indications for use

Hypertension (persistent rise in blood pressure).

Dosing and Administration

Assign to 0.05 g once a day. The daily dose of the drug could be increased to 0.1 g.

Side-Effects

There -golovokrugenie, ortostatical hypotension (fall in blood pressure in the transition from the horizontal to the vertical); Rarely gipercalziemia (increasing calcium in the blood), improved alanintransferzy enzyme; Very rarely, allergic reactions in the form of skin rashes.

Contraindications

Hypersensitivity to the drug, pregnancy, breast-feeding.

Form of

Answers to 0.05 g.

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