Madopar speed pills (despergiruemye)

Roman name

Madopar dispersible

The composition and the form of

1 capsule contains levodopa 100 mg and benserazida hydrochloride 25 mg; Patients in the 30 and 100 pc. , in box 1 flakon.1 tablet-200 and 50 mg respectively; Patients in the 30 and 100 pc. , in box 1 flakon.1 tablet despergiruemaya-100 and 25 mg respectively; Patients in the 30 and 100 pc. , in the box one bottle.

Farmakodinamika

Levodopa decarbauxiliruetsa rapidly in the brain and peripheral tissues with the formation of dopamine, the accumulation of the last bazalnah gangliah reduces symptoms parkinsonizma. Dofamin peripheral causes numerous side effects. Benserazid by blocking peripheral decarboksilazu hinders his education.

Indications

All forms parkinsonizma than pharmaceuticals.

Contraindications

Heavy urological diseases of the cardiovascular and endocrine systems, liver, kidneys; Psychosis, heavy psihoneurozy, zakratougolnaya glaucoma, pregnancy, age (prior to the completion of the entire period of growth-25 years).

Side-Effects

Anorexia, nausea, vomiting, cardiovascular disorders (arrhythmia, ortostatical gipotenzia), mental disorders (insomnia, ajitation, depression), spontaneous movement (or horeicski atetoznogo type), the increase in the aminotransferaz and alkaline phosphatase, haemolytic anaemia, moderate lakopenia and thrombocytopenia.

Patient interaction

Do effect simpatomimeticakih funds; Weakens (mutually), and doses of vitamin B_6. Compatible with others. противопаркинсоничес кими means incompatible with neselektivei MAO inhibitors in narkoznami means, R22, alothane (reception drug to be stopped for 12-48 hours before narcosis).

Precautions

During treatment nursing mothers should stop breast-feeding.

Dosing and Administration

Inside, at the time of delivery (zapiwati enough liquid). Treatment starts with the admission of 50 mg levodopa +12.5 benserazida mg 3-4 times a day. Daily dose increase at 1 single dose every week until the best. The best effects are achieved, as a rule, with a daily dose of 800-mg levodopa + 100-200 mg benserazida taken three or more receptions. Supporting dose-1 caps. to 125 mg 4-6 times a day.

Storage conditions

List B. The temperature is not above 25 ° C

Shelf life

3 years

The registration

009,524 (Ann.2001)

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