Directory Intermedianta Dofaminomimetiki Nair
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Nair

See also Selegiline

Roman name

Niar #

The composition and the form of

1 tablet contains selegilina 5 mg; blistere in 10 pcs. , in box 3 blisters or in a package of 100 pcs.

Of drugs

Simpatomimeticescoe. Does MAO-B, improving concentration in the tissues of the brain mediator monoaminov, incl. start.

Clinical pharmacology

Effective as a second-line treatment in patients parkinsonizmom on extended levodopou receiving combined (or without) with a cotton decarboksilaza (while lowering treatment).

Indications

Parkinson disease.

Pregnancy and lactation

Not recommended.

Contraindications

Hypersensitivity, arterial hypertension, feohromotsytoma, diffuse tireotoksicski goitre zakratougolnaya glaucoma, prostate adenoma cancer (with a delay of urine), tachycardia, irregular, heavy stenocardia, psychosis, dementia.

Side-Effects

In combination with levodopa, dizziness, headache, fatigue, a sense of fear, anxiety dwigatelnoe, causing insomnia, diskinesia, gipotenzia, oedema, dry mouth, loss of appetite, nausea, constipation; Rarely sputannosti consciousness, psychosis, painful craving for urinating, dizziness, increased levels of liver enzymes, skin rashes.

Patient interaction

Incompatible with fluoksetinom, simpatomimetikami, deprimirutmi drugs, alcohol. Amantadine and antiholinergicakie drugs increase the frequency of adverse events.

Overdosing

The symptoms - headache attacks, hypertonic kriz (dose of more than 60 mg per day in combination with consumption tiraminsoderjath foods). Treatment-symptomatic (specific antidote no).

Precautions

Do not appoint sick with a stomach ulcer or duodenal ulcer, as well as receiving the drugs. It should be borne in mind that the possibility of getting the machinery or vehicles. Do not assign fluoxetin earlier than 14 days after the Niara.

Dosing and Administration

The inside is not liquid, squeezed water on the table 1-2. morning (after breakfast) or 1 table. after breakfast and 1 table. afternoon (daily dose should not exceed 10 mg), in combination with individually tailored dose of levodopa.

Storage conditions

table. : List B. The temperature is not above 25 ° C

Shelf life

table. : 3 and

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