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NairSee also SelegilineRoman nameNiar #The composition and the form of1 tablet contains selegilina 5 mg; blistere in 10 pcs. , in box 3 blisters or in a package of 100 pcs.Of drugsSimpatomimeticescoe. Does MAO-B, improving concentration in the tissues of the brain mediator monoaminov, incl. start.Clinical pharmacologyEffective as a second-line treatment in patients parkinsonizmom on extended levodopou receiving combined (or without) with a cotton decarboksilaza (while lowering treatment).IndicationsParkinson disease.Pregnancy and lactationNot recommended.ContraindicationsHypersensitivity, arterial hypertension, feohromotsytoma, diffuse tireotoksicski goitre zakratougolnaya glaucoma, prostate adenoma cancer (with a delay of urine), tachycardia, irregular, heavy stenocardia, psychosis, dementia.Side-EffectsIn combination with levodopa, dizziness, headache, fatigue, a sense of fear, anxiety dwigatelnoe, causing insomnia, diskinesia, gipotenzia, oedema, dry mouth, loss of appetite, nausea, constipation; Rarely sputannosti consciousness, psychosis, painful craving for urinating, dizziness, increased levels of liver enzymes, skin rashes.Patient interactionIncompatible with fluoksetinom, simpatomimetikami, deprimirutmi drugs, alcohol. Amantadine and antiholinergicakie drugs increase the frequency of adverse events.OverdosingThe symptoms - headache attacks, hypertonic kriz (dose of more than 60 mg per day in combination with consumption tiraminsoderjath foods). Treatment-symptomatic (specific antidote no).PrecautionsDo not appoint sick with a stomach ulcer or duodenal ulcer, as well as receiving the drugs. It should be borne in mind that the possibility of getting the machinery or vehicles. Do not assign fluoxetin earlier than 14 days after the Niara.Dosing and AdministrationThe inside is not liquid, squeezed water on the table 1-2. morning (after breakfast) or 1 table. after breakfast and 1 table. afternoon (daily dose should not exceed 10 mg), in combination with individually tailored dose of levodopa.Storage conditionstable. : List B. The temperature is not above 25 ° CShelf lifetable. : 3 and |
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