Arius

Roman name

Aerius #

The composition and the form of

1 tablet coated liner desloratadina contains 5 mg; blistere in 7 or 10 pcs. , in the box one blister.

Of drugs

The anti, противовоспалительно е. Yes blocks peripheral gistaminove N_1-retseptora and suppresses cascade cytotoxic reactions (that Cytokines IL_4, IL_6, IL_8, IL_13, hemokinov type RANTES, products superoxidnyi anion activated polimorfnoyadernami neitrofilami, adhesion and chemotaxis Eosinophils, expression of adhesion molecules, including R-selektina etc.).

Pharmacokinetics

Bioavailability proportional to the dose (in the range of doses of 5 and 20 mg). Defined plasma within 30 min after administration. C_max plasma after a single admission to the dose of 5 or 7.5 mg achieved through plasma at 2-6 Associated with the plasma protein to 83-87%. T_1/2 - 20-30 hours It permeates through GEB passes through the placental barrier, breast milk. Metabolised in the body by gidrauxilirovania glukuronirovania and it shows with urine (less than 2% in unmodified form), and faeces. Not removed without gemodialise.

Indications

Seasonal allergic rhinitis (mild symptoms such as sneeze, rinorea, zalojennosti nose, itching in the nasal cavity and the sky, cough, itching and red eyes, slezotechenie), the removal of itching and rashes with chronic idiopathic krapiwnice.

Pregnancy and lactation

Contraindicated in pregnancy, as safety and efficacy have not been established. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, pregnancy, breast-feeding.

Side-Effects

Rarely, headache, fatigue, dry mouth.

Patient interaction

Clinically meaningful interaction with ketokonazolom eritromitinom and have not been identified.

Overdosing

Symptoms : Symptoms increased by Reackzi.lechenie : symptomatic therapy.

Precautions

There is a need to carefully designate of renal failure. It should refrain from the use in paediatric practice, since safety and efficacy of their use in children has not been quantified.

Dosing and Administration

Inside, regardless of the meal, not liquid, water teenagers, adults and children over the age of 12 years, 5 mg / sut.

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