Gistaglobin

Roman name

Histaglobin

The composition and the form of

1 bottle with liofilizirovannam powders for the preparation of injection solution contains :-Gistaglobina normal human immunoglobulin 12 mg, gistamina dihydrochloride 0.00015 mg, sodium thiosulphate 32 mg; Gistaglobina bowl-normal human immunoglobulin 36 mg, gistamina dihydrochloride 0.00045 mg, sodium thiosulphate 32 mg; complete with one vial solvent (2 ml of water for injection), in a cardboard box on the bottle 3 and 3 mg.

Of drugs

Противоаллергическое . It stimulates the development of antibodies to gistaminu.

Farmakodinamika

Increases ability inachtivirovti serum free histamine; Degranulatia suppresses peritoneal fat cells and prevents the release gistamina of them reduces gistamina release from the oppression Ige-oposredovanna bazofilov reactivity.

Clinical pharmacology

Therapeutic effectiveness (including the dramatically changing environmental conditions) in patients round allergic rhinitis is 95%, with chronic retidiviruta krapiwnica-82%, with неинфекционно-аллерг��ческой bronchial asthma, I point light currents to 90%.

Indications

Allergic different origins : respiratory (bronchial asthma, senna fever season (year), allergic rhinitis), skin (eczema and urticaria, including chronic form neirodermit), neurological (certain forms of migraine); Some forms fifth paragraph syndrome, etc.

Pregnancy and lactation

Contraindicated (safety of the pregnancy is not known). Since some of gistaglobina made with milk, breastfeeding at the time of treatment must stop.

Contraindications

Гиперчувствительност ь to savorotocnam protein (makers, plasma, etc.); infection (local, generalized), exacerbation of asthma, eczema, etc., selective IgA deficit.

Side-Effects

COPD disease after 1-2 injections, the pain at the (alleged simptomaticakimi means).

Patient interaction

Compatible with protiwallergicaka (local, system), and non-desencibiliziruta therapy.

Overdosing

Even with the introduction of daily medication, there has been no events overdoses.

Precautions

Before treatment recommended the therapy of local or systemic infections. The issue / 386/1989

Dosing and Administration

P / or to the in / m (powder mixtures and introduce immediately). Average chart a course of treatment : 6-9 injection of 2 ml, with an interval of 2-3 days gistaglobina and 6 injection of 2 ml at intervals of 3-7 days gistaglobina triplex; One month to repeat a course of three injections, followed by monthly injection for 3 or 6 Mexiatsev.pri seasonal allergies : wise to start treatment before the season (tips plants), with the aim of prevention and subsequent injection drug during the critical season; in predmenstrualnom syndrome allergic nature-one injection at 6, 13 and 20 day menstrual cycle, followed by injections for each 20 day menstrual Zikla.nizkie dose (gistaglobin) is particularly encouraged to nominate children and adolescents, higher doses (gistaglobin triplex) are increasingly fraught with asthma, severe pollinoza or chronic recidivating allergic diseases, as well as in patients with the lack of positive impact from the first-rate (one) treatment.

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