Loratadin 10-sle

Roman name

Loratadine 10-SL

The composition and the form of

1 tablet contains loratadina 10 mg and auxiliary substances, lactose, cells, calcium stearate; in a contour acheikova packing 10 pcs. , in box 1, or 3 packaging.

Of drugs

Antigistaminnoe, противоаллергическое . Does gistaminove H_1-retseptora.

Pharmacokinetics

Well drawn from the blood. Activity begins in 30 minutes and lasts for 24 hours Metabolised in the liver, with the participation of zitohroma P450 c education metabolita active - дескарбоэтоксилората дина. C_max loratadina and its active metabolita plasma achieved through 1.3 and 2.5 h, respectively. T_1/2 loratadina-8 p, дескарбоэтоксилората дина around 28 pm

Farmakodinamika

It is awake and does not affect the psychomotor functions mind fitness, mental activity.

Indications

Allergic rhinitis (seasonal, year-round), allergic rinokongunguit, chronic idiopathic urticaria, allergic zudaschie Medicine, allergic contact dermatitis, chronic eczema (the Integrated Management).

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Гиперчувствительност ь (including its components), pregnancy, breast-feeding, child up to 2 years.

Side-Effects

From the nervous system and sensory organs : headache, fatigue, fever Whobudimosti.so part of the intestine : dry mucous membranes of the mouth, nausea, vomiting, гастрит.Аллергически�� reactions : skin rash.

Patient interaction

Erythromycin, zimetidin, ketokonazol increase the concentration of plasma.

Overdosing

Symptoms : drowsiness, tachycardia, headache Bol.lechenie : washing stomach, the appointment of Findings and laxatives of activated carbon.

Precautions

Caution must be exercised while applying drugs inhibiting system zitohroma P450.

Dosing and Administration

Inside. Adults and children over the age of 12-10 mg once a day, daily intake to 10 mg. Children 2-12 years : weighing less than 30 kg, 5 mg once a day, daily intake to 5 mg, more than 30 kg to 10 mg once a day, daily intake to 10 mg. Against the backdrop of the liver initial dose of 5 mg / sut.

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