Mebhydrolin

Chemical name

2,3,4,5-Тетрагидро-2-мети��-5-(фенилметил)-1H-пирид о[4,3-b]индол

Gross

C19-H20-N2

Characteristics

White or white with blue polka crystalline powder. Virtually nerastvorim in water and organic solvents.

Of drugs

The drugs-antigistaminnoe, protiwallergicescoe, protivozudnoe, antiekssoudativoe. Does gistaminove H_1-retseptora lowering the tone smooth muscles (bronchi stomach, womb), reduces the permeability of capillaries and pain, warns a break. Weak m-holinoretseptora blocks, it is expressed sedative and hypnotic effect (permeates through GEB, to a small extent). The effect could be as high as 48 hours.

Indications

Allergic rhinitis (seasonal, chronic), pollinoz, allergic conjunctivitis, urticaria, eczema, skin reaction to insect bites; Combination therapy zudath dermatosis and bronchial asthma.

Restrictions on the use of

Zakratougolnaya glaucoma, pilorostenoz, epilepsy, the heart rhythm.

Contraindications

Hypersensitivity, saying disease stomach and duodenal ulcer (in the phase of deterioration), inflammatory diseases decreases, Denmark prostate gland.

Side-Effects

From the nervous system and sensory organs : increased fatigue, dizziness, parestesia; In the use of high doses of a slow reaction speed, drowsiness, and lack of visual perception, the child paradoxical reactions : irritability, anxiety, insomnia, Tremor.so part of the intestine : seldom-dry mouth, nausea, heartburn, irritation of mucous membrane stomach, pain in epigastralna areas of diarrhoea, vomiting, Zapor.so the urinary system : the Mocheispuskania.so part of the blood : rarely granulozitopenia, agranulozitos.

Patient interaction

Do the funds oppressive central nervous system.

Precautions

Be wary designate of pregnancy and breastfeeding. Caution is also required in the use of a liver disease and kidney (correction possible doses and spacing of meals). Be wary designate of pregnancy and breastfeeding, as well as patients with potentially hazardous activities that require increased attention and psychomotor speed reactions.

Dosing and Administration

Inside (after delivery). Adults and children over 10 years - 200 mg 1-2 times a day; Maximum dose : single 300 mg daily, 600 mg; Children 5 to 10 years, 200 mg / day, from 2 to 5 years, 50 mg / day, up to two years in the 50-100 mg / sut.

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