Sequifenadine

Chemical name

альфа,альфа-Ди-о-толил -3-хинуклидинметанол (as hydrochloride)

Gross

C22-H27-N-O

Characteristics

Derived hinoklidilkarbinola. White or white with a slightly kremovatam white crystalline powder, odourless. Very little is soluble in water, easily soluble in methanol, it is difficult soluble in ethanol, little in chloroform.

Of drugs

The drugs-antigistaminnoe, противоаллергическое . Is antagonist N_1-gistaminovh receptors, blocking serotoninove 5-nt_1-retseptora.

Indications

Allergic eye, skin, including allergic and atopic dermatitis, vasculit; pollinoz, allergic rhinitis, and rinosinusopatia reaction (in the face of personal, food, the home, etc.); neirodermit, red flat zoster.

Pregnancy and lactation

Contraindicated in pregnancy.

Contraindications

Violation of the kidney pregnancy.

Side-Effects

Brown mouth, diarrhoea phenomenon increased appetite, gastralgia, drowsiness.

Precautions

It should not be used in conjunction with the drivers of vehicles and people skills relate to the high concentration of attention.

Dosing and Administration

Inside, the food adult for 0.05-0.1 g 2-4 times a day. The maximum daily intake of 0.4 and supporting dose-0.05 g twice a day. The course of treatment is 15 days.

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