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Telfast

See also Fexofenadine

Roman name

Telfast

The composition and the form of

1 tablet coated liner contains feksofenadina 112 or 168 mg (as feksofenadina hydrochloride 120 or 180 mg respectively); blistere in 10 pcs. , in box 1, 2 or 3 blisters.

Pharmacokinetics

Rapidly absorbed reaches C_max after 1-3 hours Mean C_max after taking 120 and 180 mg - 427 ng / ml and 494 ng / ml, respectively. 60-70% binds to plasma proteins. Is pharmacologically active metabolite. Is partial vnepechenernmu metabolizmu. T_1/2 after taking multiple doses 11 hours Write mainly jelchew in urine (up to 10% in an unmodified form), and faeces.

Clinical pharmacology

After intake of 10 to 130 mg therapeutic effect is a one hour is the maximum in 6900 and continued for 24 hours For a more long-term effects must be taken at least 130 mg.

Indications

Allergic disease (seasonal allergic rhinitis, urticaria).

Pregnancy and lactation

Allowed where the potential benefits for a mother than the potential risk to the fetus. During treatment should stop breastfeeding.

Contraindications

Hypersensitivity, the children's age (up to 12 years).

Patient interaction

Erythromycin and ketokonazol added effect. It interacts with omeprazolom (the interval between admission and antatsidov feksofenadine shall not be less than two hours).

Precautions

To use caution if there is a violation of the functions of the liver or kidney. During treatment should check individual responses to the work requiring high concentration (driving vehicles work with).

Dosing and Administration

Inside, adults and children over the age of 12 years, 1 tab. (120 or 180 mg) once a day.

Storage conditions

At room temperature

Shelf life

3 years

The registration

010711

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