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TirlorSee also LoratadineRoman nameTirlor #The composition and the form of1 tablet contains loratadina 10 mg; blistere in 10 pcs. , in a cardboard bundle one blister.Of drugsThe anti, antigistaminnoe, antiekssoudativoe, protivozudnoe. Selectively blocking H_1 -gistaminove receptors and prevents the gistamina the smooth muscles and blood vessels, reduces the permeability of capillaries, slows exudation, reduces itching.PharmacokineticsWell drawn from the blood. C_max blood through a 1,3-2,5 hours Biotransformiroetsa in the liver with the formation of the active metabolita descarboetauxiloratadina, displayed with the urine within 24 hours Penetrates into breast milk.FarmakodinamikaThe effect is 30 minutes after taking 1 and lasts for 24 hoursIndicationsAllergic rhinitis (seasonal and year-round), allergic conjunctivitis, pollinoz, urticaria, incl. chronic idiopathic, angioneuroticeski swelling, psevdoallergicakie reaction zudaschie Medicine, allergic reactions to insect stings.Pregnancy and lactationPerhaps if the effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.ContraindicationsHypersensitivity, breastfeeding, age up to 2 years.Side-EffectsFrom the nervous system and sensory organs : headache, dizziness, increased fatigability, bringing (the children). For part of the intestine : dry mouth, nausea, vomiting, gastritis, a violation Pecheni.prochie : alopecia, fever, tachycardia, allergic reactions.Patient interactionErythromycin, ketokonazol, zimetidin increase concentration.OverdosingSymptoms : headache, drowsiness, Tahikardia.lechenie : removing the drug from the stomach; Symptomatic and supportive therapy.Dosing and AdministrationInside, adults and children over 12 years of age and weighing more than 30 kg : 10 mg (1 tab). Once a day. If any of the liver, initial dose 5 mg / sut. Children from 2 to 12 years, 5 mg / day (1 / 2 table). .Storage conditionstable. : List B. In dry the dark place at a temperature of no higher than 30 ° CShelf lifetable. : 3 and |
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