Directory Intermedianta Gistaminergicakie funds Gistaminolitiki H_1-antigistaminne funds Tirlor
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Tirlor

See also Loratadine

Roman name

Tirlor #

The composition and the form of

1 tablet contains loratadina 10 mg; blistere in 10 pcs. , in a cardboard bundle one blister.

Of drugs

The anti, antigistaminnoe, antiekssoudativoe, protivozudnoe. Selectively blocking H_1 -gistaminove receptors and prevents the gistamina the smooth muscles and blood vessels, reduces the permeability of capillaries, slows exudation, reduces itching.

Pharmacokinetics

Well drawn from the blood. C_max blood through a 1,3-2,5 hours Biotransformiroetsa in the liver with the formation of the active metabolita descarboetauxiloratadina, displayed with the urine within 24 hours Penetrates into breast milk.

Farmakodinamika

The effect is 30 minutes after taking 1 and lasts for 24 hours

Indications

Allergic rhinitis (seasonal and year-round), allergic conjunctivitis, pollinoz, urticaria, incl. chronic idiopathic, angioneuroticeski swelling, psevdoallergicakie reaction zudaschie Medicine, allergic reactions to insect stings.

Pregnancy and lactation

Perhaps if the effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, breastfeeding, age up to 2 years.

Side-Effects

From the nervous system and sensory organs : headache, dizziness, increased fatigability, bringing (the children). For part of the intestine : dry mouth, nausea, vomiting, gastritis, a violation Pecheni.prochie : alopecia, fever, tachycardia, allergic reactions.

Patient interaction

Erythromycin, ketokonazol, zimetidin increase concentration.

Overdosing

Symptoms : headache, drowsiness, Tahikardia.lechenie : removing the drug from the stomach; Symptomatic and supportive therapy.

Dosing and Administration

Inside, adults and children over 12 years of age and weighing more than 30 kg : 10 mg (1 tab). Once a day. If any of the liver, initial dose 5 mg / sut. Children from 2 to 12 years, 5 mg / day (1 / 2 table). .

Storage conditions

table. : List B. In dry the dark place at a temperature of no higher than 30 ° C

Shelf life

table. : 3 and

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