Atilok

Roman name

Aciloc

The composition and the form of

1 tablet contains ranitidine hydrochloride 150 or 300 mg; in a box 10 blisters to 10 st.1 USD 2 ml solution for injection 50 mg; in a Box 5 pcs.

Of drugs

Protivoyazvennoe. Does gistaminove H_2-retseptora parietalnah cells mucous membrane stomach, oppressing and basal stimulirovannuyu secretion of hydrochloric acid. Reduces pH of stomach contents, and thereby reduces pepsina activity.

Pharmacokinetics

C_max through 1-2 hrs (regardless of the meal). Bioavailability of 50%. Linking blood plasma proteins is 15%. Partly metabolised in the liver. Excreted kidneys. T_1/2-2 p.m.

Indications

Ulcers disease stomach and duodenal ulcers, ulcers (symptomatic, Post) syndrome Zollinger-Ellison, reflux-ezofagit. Prevention gastrointestinal bleeding caused by stress recidivating bleeding from chronic ulcers, Mendelssohn syndrome (acid aspiration of stomach contents during anaesthesia or childbirth).

Pregnancy and lactation

During pregnancy, are acceptable as long as the benefits to the mother outweighs the potential harm to the foetus. For the period of treatment to stop breast-feeding.

Contraindications

Гиперчувствительност ь.

Side-Effects

Headaches, increased fatigue, dizziness, aetiology, AV blockade allergic reaction (urticaria).

Precautions

Patients with violations of the kidney medication should assign to a lower dose.

Dosing and Administration

Inside. Ulcers disease stomach and duodenal ulcers in the phase of deterioration : 150 mg twice per day or 300 mg once per day overnight. Exchange-4-8 Ned.v / in or / m. Prevention recidivating bleeding caused by stress : 50-100 mg (2-4 ml) every 6-8 C.prophylactika syndrome Mendelssohn : 50 mg (2 ml) for 45 to 60 min; To narcosis, or at the beginning of, or during childbirth.

Storage conditions

r-r d / in. : List B. In a cool dry place so that the temperature does not exceed 30 ° Ctabl.p.o. : In dry the dark place at a temperature of 15 ° C

Shelf life

r-r d / in. : 2 g.tabl.p.o. : 3 and

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