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GastrosidinSee also FamotidineRoman nameGastrosidinThe composition and the form of1 tablet coated liner contains famotidine 40 mg; in the package three blisters on 10 pcs.Of drugsProtivoyazvennoe. Does gistaminove H_2-retseptora.PharmacokineticsOnce inside C_max plasma-by 1-3.5 hrs, tying with the squirrels - 15-22%. Bioavailability - 37-45%, the volume of distribution calculated l / kg Income from the body via the urine and jelchew, about 25-30% displayed product with urine in an unmodified form. In patients with normal kidney function T_1/2 - 2.5-4 hoursClinical pharmacologyAfter one reception effect lasts 12 hours It stops the hydrochloric acid in their stomachs (as bazalnoe or UV pentagastrinom, tetragastrinom or betazolom). A 40 mg once a day Gastrosidin night reduces the secretion by an average of 94%. Is scarring of stomach ulcer and duodenal ulcer. No impact on monooksigenazna activity of the liver and on the secretion of prolactin, no antiandrogennogo action.IndicationsPeptic ulcer and duodenal ulcers Good stomach (prevention of complications and treatment), pathological conditions associated with increased Pepsi (incl. syndrome Zollinger-Ellison).ContraindicationsГиперчувствительност ь.Side-EffectsHeadache, dizziness, the orientation, constipation, increased transaminaz in whey.PrecautionsPrior to the treatment necessary to be sure 12.5.1 ulcer. Pregnant and after childbirth designate with a strong testimony and supervised by a doctor.Dosing and AdministrationInside, for the treatment of ulcers and gastric duodenal ulcer-40 mg per night for up to four weeks (in the absence of effects to 8 weeks), for the prevention of acute-20 mg per night for 6 months in the syndrome Zollinger-Ellison-20 mg every 6 h (maximum daily dose is 400 mg).Storage conditionstabl.p.o. : List B. |
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