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RanigastSee also RanitidineRoman nameRanigastThe composition and the form of1 tablet coated liner contains ranitidine (as hydrochloride), 75 or 150 mg; in a contour acheikova packing 10 pcs. , in a cardboard unit 1, 2 and 6 packages respectively.PharmacokineticsExtracted from the blood of 50% of meals or antatsidov. C_max (478 µ g / ml) is a 95 hour T_1/2 - 2h The distribution - 1.53 l / kg Penetrates the GEB and breast milk, creating the concentration close to the plasma (25-100%). Metabolised in the liver by oxidation (nitrogen and sulphur) and demethylation (1%). Excreted kidneys.IndicationsUlcers disease stomach and duodenal ulcers (treatment and prevention), the syndrome Zollinger-Ellison, reflux-ezofagit, erosive ezofagit after diagnostic manipulation. Ranigast (75 mg), giperatidnaya neuralgia (heartburn, acid burp, etc.).ContraindicationsHypersensitivity, pregnancy, breast-feeding, age and 12 years of age.Patient interactionIncreases (50%) of metoprolola plasma and increases its T_1/2 from 4.4 to 6.5 hours Smoking weakens.PrecautionsBefore treatment should be deleted malignant processes in the digestive tract. Caution is needed if there is a violation of the functions of the liver and kidney, acute porfirii (incl. history). Be wary of during the drivers of vehicles and people skills relate to the high concentration of Vnimania.esli dispepsii symptoms do not pass within two weeks of treatment Ranigastom (tabl.75 mg), should see a doctor.Storage conditionsList B. In a dry, the dark spotShelf life3 yearsThe registration013977/01 |
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