Ranitidine sediko

Roman name

Ranitidine SEDICO

The composition and the form of

1 tablet coated liner contains ranitidine (as hydrochloride), 150 or 300 mg; blistere in 10 pcs. , in box 2 or 1 blister respectively.

Of drugs

Protivoyazvennoe. Does gistaminove H_2-retseptora reduces the secretion of hydrochloric acid and pepsina.

Pharmacokinetics

Rapidly absorbed from the digestive tract. C_max plasma achieved in 2-3 hours, tying with the plasma protein-10-19%. It crosses the placental barrier, poorly-by GEB. T_1/2 - 3h The urine output 27-39%, unedited, (within 24 hours), and 6-10% in the form of metabolites and the remainder from jelchew. The Cl-700 ml / min.

Farmakodinamika

Suppress basal and stimulirovannuyu secretion of hydrochloric acid, reduces the acidity and gastric juice. Duration of the single-admission 12 hours

Indications

Ulcers disease stomach and duodenal ulcers (including associated with the admission NPVS) reflux-ezofagit, erosive ezofagit, syndrome Zollinger-Ellison, the Post and "stressful" stomach ulcers, relapse prevention bleeding from the upper gastrointestinal divisions aspiration and gastric juice during narcosis (Mendelssohn syndrome).

Pregnancy and lactation

Contraindicated.

Contraindications

Hypersensitivity, pregnancy, breast-feeding, age and 14 years of age.

Side-Effects

Headache, dizziness, drowsiness, insomnia, sputannosti consciousness, hallucinations, lakopenia, thrombocytopenia, increased prolactin plasma, ginekomastia, amenorea, impotence, reduced libido, alopecia, streams functional liver tests, a slight increase in creatinine in the serum.

Patient interaction

Antatsida and sukralfat may reduce absorption (break between reception products shall not be less than two hours).

Precautions

The appointment should be deleted malignant neoplasms in oats, stomach and gastrointestinal bleeding. To use caution in case of the kidneys and liver. Termination reception should gradually (possible relapse ulcers).

Dosing and Administration

Inside, adults with ulcers stomach and duodenal ulcers : for the treatment of acute for the 150 mg twice a day (morning and evening), or 300 mg per night for 4-8 weeks, if necessary, to 300 mg twice a day; Prevent attacks on the 150 mg evening, before Snom.azwa of hosting NPVS : 150 mg twice a day or 300 mg evening, at night, for a period of 8 to 12 weeks, for the prevention of ulcers on 150 mg twice �утки.Послеоперационн ые Global : 150 mg twice a day for 4-8 �ед.Желудочно-пищевод��ая refluksnaya disease : 150 mg twice a day or 300 mg per night (up to 150 mg four times a day) for a 8-12 Ned.sindrom Zollinger-Ellison : initial dose of 150 mg three times a Sutki.prophylactika recidivating bleeding : 150 mg twice a Sutki.prophylactika syndrome Mendelssohn : eve of the operation (evening), and two hours in advance of narcosis-150 Mg.patientam with renal insufficiency with Cl creatinine less than 50 ml / min, 150 mg a day.

Directory → Intermedianta → Gistaminergicakie funds → Gistaminolitiki → H_2-antigistaminne funds → Ranitidine sediko