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ZantinSee also RanitidineRoman nameZantinThe composition and the form of1 tablet coated liner contains ranitidine hydrochloride equivalent of 0.15 grams of ranitidine - 0.168 g; in the package 10, 20, 40 or 60 st.1 ml solution for injection 2.5% of ranitidine hydrochloride (in terms of 100% of ranitidine) 0,025 g; USD in 1 or 2 ml, in a contour acheikova package 5 ampoules, in a cardboard unit 1 or 2 packaging.Of drugsProtivoyazvennoe. Axura N_2-gistaminovh receptors II generation. Suppress basal and stimulirovannuyu gistaminom, gastrinom, azetilholinom secretion of hydrochloric acid. Impact pepsina activity. Duration of the 12 hoursIndicationsUlcers disease stomach and duodenal ulcers, giperazidne state stress ulcers, erosive reflux-ezofagit, Npvs-gastropatia, syndrome Zollinger-Ellison, chronic episodes dispepsii, prevention Mendelssohn syndrome, acute ulcers, gastric aspiration juice during narcosis, the recurrence of bleeding in the aftercare period.Pregnancy and lactationContraindicated in pregnancy.ContraindicationsHypersensitivity, pregnancy.Side-EffectsFrom the nervous system and sensory organs : headache, dizziness, sputannosti consciousness, hallucinations, the lack of visual perception, the ccomodation Glaza.so the circulatory system and blood (blood, gemostaz) : aetiology, Av-blokada, asistolia Arterial gipotenzia, leiko- and trombopenia, agranulozitos, pancitopenia, hypothetical aplasia and bone Mozga.so the stomach : reversible changes in the functional liver tests, hepatitis, �анкреатит.Аллергичес кие reactions : skin rash, urticaria, angioneuroticeski swelling, anaphylactic shock, Bronhospazm.prochie : artralgia, mialgia, giperprolaktinemia, ginekomastia, amenorea weakening Yeah.Patient interactionSuction violate sukralfat and other antatsida. Ranitidine accelerates induction zefalosporinov, hlorpromazina, indometacin, ketokonazola, oppressing metabolism in the liver fenazola, amidopirina, gexobarbitala, propranolola, diazepam, lignokaina, fenitoina, theofillina, racumin.Dosing and AdministrationInside, adults : with ulcers stomach and duodenal ulcers, for 0.15 grams twice a day or 0.3 g per night, the length of four weeks, with nerubtsuteisa nose-8 weeks; In erozivne reflux-ezofagite to 12 weeks. Preventing a recurrence of ulcers 0.15 g per night, smokers 0.3 g per night. Zolinger syndrome - Ellison on 0.15 grams three times a day with a maximum dose of 6 g / sut. Children : 2-4 mg / kg twice a day with a maximum daily dose of 0.3 and the renal failure (Cl creatinine less than 50 ml / min), 0.15 g / Sut.vesroslam : in / in the slow (50 mg for 2 min) in 20 ml of 0.9% solution of sodium chloride. In / in drip with 25 mg / hr for 2 hrs If necessary, re-introduction of every 6-8 hours V / m at 0.05 g 3-4 times a day. Preventing bleeding from the intestine : in / in slowly in the initial dose of 0.05 g followed in / with the introduction of bacterial 0,125-0,25 mg / kg / h or combination of 0.15 g (Table 1). Twice a day. Children : 2-4 mg / kg twice a day with a maximum daily dose of 0.3 and the renal failure (Cl creatinine less than 50 ml / min), 25 mg / sut.Storage conditionsr-r d / in. : List B. In dry the dark place at a temperature of no higher than 25 ° Ctabl.p.o. : In dry the dark place at a temperature of no higher than 25 ° CShelf lifer-r d / in. : 3 g.tabl.p.o. : 3 and |
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