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Primalan

See also Mequitazine

Roman name

Primalan #

The composition and the form of

delimaya one tablet contains mekvitazina 5 or 10 mg; in a contour acheikova packing 14 pcs. , in a cardboard bundle one package.

Of drugs

The anti, protivozudnoe, antiekssoudativoe. Does gistaminove H_1-retseptora. It prevents the release of fat cells biologically active substances. Provides antiholinergicescoe little effect.

Pharmacokinetics

Quickly and almost completely absorbed from the digestive tract. Away reduces speed removals, but did not affect its value. C_max after a single reception 5 mg achieved a 3.2 h is 3.26 ng / J It passes through GEB. Metabolised in the liver with the formation of the pharmacologically active metabolites. T_1/2 - 1830 Report mostly in faeces (in the form of metabolites and unaltered), a small number in an unmodified form Pockami.actie evident after 30 minutes and lasts for 24 hours

Indications

Allergic rhinitis (seasonal and year-round) and conjunctivitis, urticaria (acute or chronic retidivirutaya), atopic dermatitis.

Contraindications

Гиперчувствительност ь components products and other derivatives fenotiazina, zakratougolnaya glaucoma, clean giperplazia prostate cancer, simultaneous MAO inhibitors.

Side-Effects

From the nervous system and sensory organs : drowsiness, headache, a feeling of tiredness, emotional lability in older patients and Detei.so part of the intestine : dry mouth, diarrhoea phenomenon.

Patient interaction

Together with the admission atropinom, tricyclic andidepressantami (imipramin etc.), antiholinergicakimi противопаркинсоничес кими means miotropnami spazmolitikami, dizopiramidom, antipsychotic means fenotiazina derivatives may increase side effects. Do the gipotenziveh funds and, oppressive central nervous system (drugs with sedative effects, barbiturates, benzodiazepines, clonidine, hypnotics, analgesics, central and protivokashleve antipsihoticalkie PP).

Overdosing

Symptoms : increased by Effectov.lechenie : washing stomach, symptomatic therapy.

Precautions

Not recommended award (when necessary to be extra caution) in pregnancy, breastfeeding, children up to 6 years. Be wary, patients with liver failure (risk cumulation), and older patients, individuals at zaporam in Epilepsii.s use caution during the drivers of vehicles and people skills relate to the high concentration of attention.

Dosing and Administration

The inside is not liquid, squeezed water, regardless of the meal. Adults and children over 12 years of age, 5 mg twice a day (morning and evening), or 10 mg once Vecerom.detam from 6 to 12 years : body mass index of less than 30 kg (6-10 years) 2.5 mg twice a day (morning and evening) 30 to 40 kg (10 to 12 years), 2.5 mg morning and 5 mg evening, or 7.5 mg one evening. The course of treatment is a doctor.

Storage conditions

tabl.del. : In the dark place at a temperature of no higher than 25 ° C

Shelf life

tabl.del. : 3 and

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