Tranilast

Chemical name

2-[[3-(3,4-Диметоксифенил) -1-оксо-2-пропенил]амин��]бензойная acid

Gross

C18-H17-N-O5

Of drugs

Drugs, the cell, bronhodilatirtee, противоаллергическое . 4-3 membranes fat cells ingibiruet gialuronidazu. Lock антиген-стимулирован��ый Sign calcium ions in tucnuu space, and protects degranulatia releases allergy mediators (histamine, lakotriena and other biologically active substances). Warn of allergic reactions immediate type of rapidly increasing capillary permeability, development oedema, spazmom smooth muscles, including bronchus. Stops adhesion cells caused by substance R. Effectiven mostly with bronchial obstruction and diseases in the pathogenesis of which is essential to allergic component. Oppressing synthesis of collagen and fibroblastami interleikina-1 cells inflammation. It stops cell proliferatiou. The studies in vitro oppressing proliferatiou and synthesis of collagen gladkomyshechnykh cells receptacles and lakotrienov products in the membrane lining the large bowel.

Indications

Bronchial asthma, atopic dermatitis, urticaria, allergic rhinitis.

Pregnancy and lactation

Contraindicated in pregnancy.

Contraindications

Hypersensitivity, violations of the liver, pregnancy.

Side-Effects

From the central nervous system : headache, Sonlivosti.so part of the intestine : dyspeptic syndrome rarely is a violation of the functions of the liver, Jeltuha.so part of the blood : rarely decrease in the number of cells and the level of Gemoglobina.so the urinary system : pollakiuria, gematuria, frequent and painful urination, zistitopodobne Simptoma.prochie : to raise transaminaz, giperbilirubinemia, skin rashes.

Dosing and Administration

Inside adult-100 mg (1 capsule) three times a day.

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