Directory → Интермедианты → Serotoninergicakie funds → Peritol
This page is translated automatically with a help of Google Translate

Peritol

See also Cyproheptadine

Roman name

Peritol

Pharmacokinetics

Quickly and completely absorbed from the digestive tract. C_max plasma achieved in the first two hours, therapeutic level remains at 4-6 Evenly distributed in the body, enters the central nervous system. Intensive metabolised (gidrauxiliruetsa followed glukuronirovaniem) in the liver. After receiving a single 4 mg 2-20% excreted through the intestine, of which 34% unaltered, not less than 40% of dose from urine mainly in the form of kongugatov glukuronova with acid. When kidney failure off slower.

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, zakratougolnaya glaucoma, clean giperplazia prostate cancer, a delay urination, predisposition to otekam, urine retention, the simultaneous application of MAO inhibitors (syrup), pregnancy, breast-feeding, child before age 6 months.

Patient interaction

When coupled with the use of ethyl alcohol and other means, oppressive CNS (sedatives, hypnotics preparations and anxiolitiki), a additivoe act with MAO inhibitors, tricyclic antidepressants increased m-holinoblokirutego actions and oppressive influence on the central nervous system, with fluoksetinom and other agricultural reverse takeover neironalnogo serotonin-lowering effect of antidepressants. Caffeine and fenamin reduce dampening effect on the central nervous system.

Precautions

Be wary appointed to cardiovascular diseases, with a history of asthma, hyperthyroidism, hypertension, children and patients older (because of the high degree of sensitivity to antigistaminnam drugs). Given the sedative effect of the admission of the first drug to do in the evening, after meals. During treatment not use alcohol. It should not be used in conjunction with the drivers of vehicles and people skills relate to the high concentration of attention.

Storage conditions

List B. The temperature 15-25 ° C

Shelf life

5 years

The registration

014084/02

All products of this group

0