Inosine

Chemical name

1,9-Дигидро-9-бета-D-рибо фуранозил-6H-пурин-6-он

Gross

C10-H12-N4-O5

Characteristics

White or white with weak yellowish white crystalline powder bitter taste, odourless. Slowly and difficult soluble in water, very little is soluble in alcohol.

Of drugs

The drugs-antihypoxia, antiaritmicescoe, anabolicescoe. It has a positive impact on the metabolic processes miocarde increases the activity of enzymes Krebsa cycle and energy balance increases the force of heartbeats and promotes greater relaxation tool in diastole (binds calcium ions trapped in zitoplazmu, at the time of commencement of cells), which has resulted in an increase in the volume of attack, improves blood circulation, incl. CABG blood circulation, reduces agregatia platelets, activates tissue regeneration (especially heart and mucous membrane syndrome). Substratno stimulates synthesis adeninovykh nucleotides.

Indications

CHD (myocardial infarction, stenocardia, of a heart rhythm), congenital and acquired heart disease, cardiomyopathy different genesis, digitalisnaya intoxication, myocarditis, liver diseases (in the face of heavy physical labour or infection and endocrine genesis), liver disease (acute and chronic hepatitis, cirrhosis, alcohol and drugs damage the liver, liver fat liver), saying disease stomach and duodenal ulcers, porphyria, tracing lakopenia (prevention).

Restrictions on the use of

Renal failure.

Contraindications

Hypersensitivity, gout.

Side-Effects

Tachycardia, the worsening gout, hyperemia and skin itch, allergic reactions.

Dosing and Administration

In / in struino or drip (40-60 drops per minute) for the 200 mg once a day, with good endurance-400 mg 1-2 times a day over a period of 10-15 days. Inside on the 0.6 g / day, for two to three days dose increase to 1,2-2,4 g / day (3 admission), a course-4-12 weeks; Uroporfirii in on the 0.80 g / sut.

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