Poly (dihydroxyphenylenethiosulfonate sodium)

Chemical name

Поли-(2,5-дигидроксифен илен)-4-тиосульфонат sodium

Gross

C6n-H4n +1- O2n +3 S2-Na

Characteristics

Powder black odourless. Easily soluble in water, virtually nerastvorim in alcohol 95% acetone, ether.

Of drugs

The drugs-antihypoxia and antioxidant. Prevents Development reactions Free oxidation and education lipid peroxides, promotes the destruction of peroxide oxidation. Characterized by a high elektronno-objemna capacity by polymerization phenolic kernels in the ortho. Antigipoksicski effect due to the structure of polifenolland hinonovogo component involved in the respiratory chain transfer electrons (shuntiruet their transport). In muthondriah maintains a high level of woven respiration and aerobic processes undermine negative effects hypoxia. In postgipoksicescom period contributed to the rapid oxidation of reduced accumulated equivalents - никотинамидадениндин уклеотидфосфата (NADF, NADFN2) optimizes the operation of normal and enhances the moist air. Increase tolerance to the physical and mental stresses. Application of the integrated endolimfaticescoy therapy (olifen in combination with antibiotic and protivovirucnam drug) in patients with pneumonia destructive and septicakimi states reduces endotokcikoz, sokpashchaet time vzdopovlenia, nopmalizuet intepfeponovy statuc and local immunologic indicators.

Indications

Reduced work when operating in extreme situations and difficult to adapt climatic conditions (Far North, mountains, etc.), chronic fatigue syndrome, injuries or surgery, krovopoteri, extensive burns, chronic obstructive pulmonary disease, bronchial asthma, lung abscesses, septic pneumonia (composed of combination therapy).

Contraindications

Hypersensitivity, the cerebral circulation, cachexia, a significant weakening of the body, pregnancy, breast-feeding.

Side-Effects

Allergic reactions (erythema, skin itch and hypotension).

Overdosing

Symptoms : nausea, discomfort in the abdomen, oppression respiratory Funktion.lechenie : symptomatic.

Precautions

There is a need to avoid rapid on / in the (possibly the hypotonia; While lowering AD should cease immediately infuziu and begin a mezaton, dobutamina or other pressornah agents).

Dosing and Administration

Inside, in / 386/1989 Inside, before or during delivery, squeezed small amounts of liquid; Adult for 0.5-1 g three times a day, the children of 0.25 g three times a day; Course duration 3-14 Dnei.v / in in the form of infusions (content sealed ex tempore dissolved in 400 ml of physiological solution, or 5% glucose solution) with a 40-60 drops in minutes, 1-3 times a day for three to five days.

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