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Dalisol

See also Uric folinate

Roman name

Dalisol

The composition and the form of

1 ml solution for injection contains calcium leikovrina 3 mg; USD in 1 and 5 ml, in the package st.1 10 ml solution for injection, 12.5 mg; Patients in 4, 24 or 28 ml, in a package 10 pcs.

Of drugs

Complementary deficit folic acid. Neutralizes antagonists folic acid.

Indications

Therapy high doses of methotrexate, metotrexatom intoxication and other antagonists of folic acid.

Contraindications

Pernitsiosnaya anaemia and other megaloblasticskie deficiency in the face of Vitamin B_12.

Side-Effects

Allergic reactions.

Precautions

When pregnancy and breast-feeding apply only as a last resort.

Dosing and Administration

V / m or / 386/1989 Adults - 10 mg / day, the children - 0.25 mg / sut. In therapy high-dose methotrexate (through 24 hours after the lifting of), 10 mg / m ^ 2 every 6 hours for 3 days, in cases of overdose, and 100 mg / m ^ 2 every 3 hours (for the contents of methotrexate in the blood drops to 10 ^ -8 M). When treating neglected cancers colon and rectum cancer, as well as cancer of breast, and 500 mg / m ^ 2 per day by continuous infusions for six days every 28 days (at least 24 hours after the appointment ftorurazila).

Storage conditions

r-r d / in. : List B. In cool the dark place at a temperature of 00 ° C

Shelf life

r-r d / in. : 2 grams.

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