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Desferal

See also Deferoxamine

Roman name

Desferal

Storage conditions

List B. At temperatures below 25 ° C

Shelf life

4

The registration

008987

Of drugs

The preparation is integrated connection to the iron. With the body removes iron from iron proteins (ferritina and gemosiderina), but not from the hemoglobin and iron enzymes. He did not change significantly in the other metals and trace elements.

Indications for use

Applied in the primary and secondary gemohromatose (violation of iron oxide), gemosideroze (dose iron yellow pigment in the skin), and in acute poisoning iron.

Dosing and Administration

The average initial dose of 1 g per day (1-2 injections); Supporting dose of 0.5 grams per day. Usually misleading injection. Implements 10% solution, which the contents of 1 ml (0.5 g) dissolved in 5 mL of sterile water for injection. Users enter only drip to a maximum rate of 15 mg / kg per hour; The maximum dose of 80 mg / kg In acute poisoning iron appoint inwards and parenteral (bypassing the digestive tract). To associate iron not vsosavchegosa from the gastrointestinal tract into a 5-10 g preparation, ie, the contents of 20 vials (dissolved in water). To remove iron vsosavchegosa impose injection of 1-2 g every 12 hours In severe cases, introducing drip suicide in one city

Side-Effects

In applying the drug may cause, in some cases, Urticaria and exantema (skin rash). Fast intravenous could lead to the collapse of (a sharp fall in blood pressure). With long-term use drugs to be before 16690 and during treatment study of the eye.

Contraindications

Pregnancy. The issuance. In sealed ampoules containing 0.5 g (500 mg) dry preparation.

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