Calcium folinate

Roman name

Calcii folinas

The composition and the form of

Liofilizirovannaya porous mass of yellow color.

Of drugs

Calzieva salt folinova acid is the antidote (antidote) in relation to drug средствамантагониста м (s opposite) of folic acid. In particular, the drug prevents and / or weaken the side effects antitumoral drug methotrexate who represses the blood. Calcium folinate contributes to the restoration of metabolism (in the body) supplements, prevents cell damage bone marrow, protects haematopoiesis (blood cells in the bone marrow), and allows the use of methotrexate for cancer chemotherapy high doses.

Storage conditions

List B. In the dark place at a temperature of no higher than 25 ° C.

Shelf life

subst. : 2 grams.

Indications for use

Applied as methotrexate antidote to prevent possible toxicity elevated, high and very high doses, as well as evolved from the usual doses of methotrexate toxic manifestations : язвенно-некротически�� stomatitis (inflammation of mucous membranes of the oral cavity with the formation of ulcers and omertveniem fabrics), enteropatii (disruption of the delicate hair), etc.

Dosing and Administration

Applied intramuscularly or intravenously struino. The use of the drug dissolved in 1 ml izotoniceski solution of sodium chloride. The solution is suitable for use in the 12-hour storage in a cool place (not more than 8 ° C).

Side-Effects

In applying calcium folinata in high doses could experience allergic reactions.

Contraindications

Pernitsiosnaya and other V12-defe-zitnye anaemia (decrease in hemoglobin in the blood associated with a lack of vitamin Vp).

Form of

Liofilizirovanny (dried by freezing vacuum) calcium folinate for injection in ampoules containing 3.24 mg (0.00324 g), or 32.4 mg (0.00324 grams) in the package to 5 million from its five vials of 2 ml izotoniceski solution of sodium chloride.

Directory → Metaboliki → Detoksicirute means, including ComSP → Calcium folinate