Cardioksan

Roman name

Cardioxan

The composition and the form of

1 bottle with liofilizirovannam powders for the preparation of injection solution contains dexrazoksana hydrochloride 500 mg; in a box one bottle.

Of drugs

Cardioproteguoe. Is similar to EDTA. In miocarde product is hydrolysis, resulting in an active connection, and then, working with iron and copper is the chelate compounds reduces the formation of the complex and doksorubitsin-gelezo oxygen radicals.

Indications

Admission antratziklinov (prevention cardiotoksicnosti) antratziklinova cardiomyopathy.

Pregnancy and lactation

Contraindicated. At the time of treatment should stop breastfeeding.

Contraindications

Pregnancy, breast-feeding (should abandon breastfeeding) гиперчувствительност ь.

Patient interaction

The drug does not affect the activity protivoopujolevu antratziklinovogo preparation.

Precautions

They should not impose without breeding. There is a need to continuously monitor hematologic indicators of liver. During infuzionna therapy Cardioksan not to be confused with any known drugs.

Dosing and Administration

B / in (treatment beginning at the same time as the introduction of the first dose antratziklina exhibition introducing throughout chemotherapy). The contents of each bottle dissolved in 25 ml of water for injection. The resulting solution (from the number of bottles) to raise 200-250 ml ringer lactate and sodium lactate. Infuziu encouraged to nominate for 40-60 minutes prior to the imposition of antratziklinov (cefuroxim Cardioksana about 15-20 minutes, followed by a break of 25 to 30 minutes). Adults - 20 mg per 1 mg / m ^ 2 antratziklina (with the usual destination). The total dose should not exceed 1000 mg / m ^ 2. Divorced solution imposed no later than 6900 after Prigotovlenia.detam 10-15 mg per Typically ^ 2 antratziklina.

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