Unitiol

Roman name

Unithiolum

The composition and the form of

White or white with a slightly yellowish sheen melkochristalliceski powder with a very light smell mercaptan. Easily soluble in water, not in the alcohol. Rastorm drug-transparent colorless liquid with a light smell mercaptan; PH 5% solution of 3,1-5,5. Sterilized at 100 ° C for 30 minutes

Of drugs

Unitiol contains two sulfgidrile group. For the preparation of approaching compleksonam (organic substances which have strong connections to the base / positive ions / metals). His active sulfgidrile group reactive with tiolovmi poisons present in the blood and tissues, and form their non-toxic (harmful) complexes, which are derived from urine. Linking poisons leads to the restoration of the enzyme systems of the body affected by the venom.

Storage conditions

subst. : List B.subst.-por. : List B.

Indications for use

Unitiol applied for the treatment of acute and chronic poisoning compounds of arsenic, mercury, chromium, bismuth and other metals belonging to the so-called tiolovam poisons, ie substances capable reactivity with sulfgidrilnami (tiolovmi), the enzyme protein, and thus the inachtivirovti (suppress activity). Less active unitiol with lead poisoning.

Dosing and Administration

For the treatment of acute and chronic poisoning with arsenic compounds and mercury entering unitiol intramuscularly or under the skin in the form of 5% aqueous solution of 5 ml (at the rate of 0.05 g product or 1 ml of 5% solution of 10 kg body mass index patient). Treatment should begin as possible before. When poisoning arsenic compounds injections made on the first day, every 6-8 hours (3-4 injections a day, depending on the patient), in the second day 2-3 injections every 12 hours thereafter according 1-2 injections a day. In poisoning by mercury injections made in the same way during the day 6-7. Children shall mean smaller doses in accordance with the age.

Side-Effects

Unitiol usually well tolerated. In some cases, there are nausea, tachycardia (ucaschenne heartbeat), a person mouth, dizziness, All these are astenia own.

Contraindications

The drug is not suitable for serious liver diseases, and hypertension (steady increase blood pressure).

Form of

5% solution in sealed to 5 ml.

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