Adenosine phosphate

Chemical name

5'-adenilovaya acid

Gross

C10-H14-N5-O7-P

Characteristics

The white crystalline powder odourless. It is soluble in water, soluble in 1% solution of sodium gidrocarbonata.

Of drugs

The drugs-sossoudorasshiratee, antiagregatine, antiaritmicescoe, metabolicescoe. Included in the kofermentov governing окислительно-восстан��вительные processes; reduces education porphyrins; briefly slows AV conduction in helping restore normal sinusovogo rhythm in patients with paroxizmalna najeludockova palpitations.

Indications

Paroxizmalnaya najeludochkovaya tachycardia (including the Wpw-sindrome), differential diagnosis najeludockovh tachiarrhythmia (tachycardia with ushirennami complexes Micro), the diagnostic электрофизиологическ ие study (the localization AV block), ischemic heart disease, chronic obliteriruty endarteriit, throm, chronic venous insufficiency, venous thrombosis; diabetic retinopathy, a disease hospital duodenal ulcers, multiple sclerosis, acute porphyria peremejatayasa lead poisoning.

Contraindications

AV blockade II and III degree or weakness syndrome sinusnogo node (with the exception of patients with artificial driver rhythm), haemorrhagic stroke, heart attack in history, pregnancy, child.

Side-Effects

Vertigo, fobia, blurred vision, headache, pain in the heart, or tahi- aetiology, AV blockade tides, metallic taste in his mouth, nausea, giperventilatia, bronhospazm, sweating, pain in the hands, back and neck.

Patient interaction

Dipiridamol reinforces effect theofillin, caffeine, etc.-xantina weaken.

Precautions

In / in a permissible only in a hospital environment, where it is possible to monitor the heart. For patients with a complicated adenosine AV blockade, if necessary, re-introduction dose should not exceed the original.

Dosing and Administration

For heavily paroxizmalna najeludockova tachycardia and diagnostic studies in / as quickly (within 2), 3 mg, in addition to 6 mg in 1-2 minutes, unless there are economies of a further 12 mg in 1-2 Min.vnutri, 0,025-0,05 g (up to 0.15 grams) per day over a period of two to four weeks.

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