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Portalak

See also Lactulose

Roman name

Portalak

Pharmacokinetics

There is absorbed from the intestine (skin not more than 3% of dose).

Farmakodinamika

The effect develops in 24-48 h after intake of

Indications

Siegenia, hepatic encephalopathy, liver precoma and coma (treatment and prevention).

Pregnancy and lactation

Data on the safety of drugs during pregnancy and lactation are not available.

Contraindications

Hypersensitivity to lactose or other sugars (lactose, galactoza) occlusion bowel rektale bleeding, or colonial ileostoma, suspicion appendix.

Side-Effects

Pain, a sense of discomfort or pain in the abdomen, diarrhoea (can be resolved lower dose), flatulence (appears at the beginning of treatment and usually goes in a few days), skin reaction (rash, etc.), nausea and vomiting (from pritorian taste drug), the vodno-elektrolitnogo balance (during long therapy high doses).

Patient interaction

When using therapeutic doses lactoulozy clinically reliable interactions with other drugs have been noted. Nevertheless, it is not recommended to take the drug within 2 h after administration of another drug. Together admission lactouloza can inachtivirovti preparations for release in the gut colon unfavourable environment (for example, preparations containing mesalazin).

Overdosing

Admission too vskih doses of the drug can cause diarrhoea loss of fluids and electrolytes, and in more severe cases, and gipernatriemia гипокалиемию.Специфи��еского antidote exists. In light of cases that product. Gipokaliemia may worsen in the liver coma, and even cause it. In that case, a potassium (potassium chloride).

Precautions

Owing to the presence of product in small amounts of sugars (15 ml syrup contain up to 1.7 grams of galactose and up to 1 g lactose) to be careful in appointing drug patients diabetes and lactose Lactozy.s caution shall mean patients gastrocardialnam syndrome : treatment start with low doses and increase them gradually to avoid Meteorizma.ne should designate product in the face of pain in the abdomen, nausea, Rvota.pri treating liver encephalopathy, especially in the initial phase of therapy, can not be used other means laxatives because. increased bowel emptying might lead to the mistaken conclusion that the appropriate dose for the therapy Engjefalopatii.esli closure is not corrected in the employment drug for a few days or condition deteriorated again after receiving the drug should be advised to Vrachu.v recommended dose of the drug has no effect on ability to drive vehicles and mechanisms.

Storage conditions

At temperatures between 10 and 20 ° C. Do not freeze due to the potential for lactoulozy crystallization.

Shelf life

3 years

The registration

015059/01-2003

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