Directory Metaboliki Enzymes and antifermenta Contrikal
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Contrikal

See also Aprotinin

Roman name

Contrykal

Of drugs

Antifibrinoliticescoe, gemostaticescoe, inhibition of proteolytic enzymes (plazmina, kinnoguenaza, trypsin, himotripsina) plasma, blood cells and tissues.

Indications

Bleeding from giperfibrinolizom, incl. after surgeries and injuries; before, during and after childbirth; hemorrhagic complications arising from tromboliticescoy therapy, acute pancreatitis, preventing postoperative pancreatitis and fat embolism.

Pregnancy and lactation

Contraindicated (I-trimester screening). At the time of treatment should stop breastfeeding.

Contraindications

Гиперчувствительност ь.

Side-Effects

From the circulatory system and blood (blood, gemostaz) : gipotenzia arterial and / or Tahikardia.so part of the intestine : nausea, Rvota.allergicakie reactions : allergic (skin rash) and anaphylacticskie (up to anaphylacticski shock) reaction.

Overdosing

Numerous tests conducted on various types of animals, even in the application of Aprotinin in doses much higher than therapeutic doses for people of any toxic effects have been detected.

Dosing and Administration

B / in (slow) struino or drip. Adult initial dose is 200000-300000 Atre, the 140,000-Atre every four hours before the normalization of hemostasis. When violations hemostasis in children agent appointed dose 14,000 Atre / kg / sut. The homemade solution for the on / in the dry substance dissolved in izotonicescom solution of sodium chloride in a ratio of one bad product : 1 USD solvent.

Storage conditions

List B. Under normal circumstances,

Shelf life

3 years

The registration

00124 (Ann.2001)

All products of this group

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