Directory → Metaboliki → Enzymes and antifermenta → Contrikal
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ContrikalSee also AprotininRoman nameContrykalOf drugsAntifibrinoliticescoe, gemostaticescoe, inhibition of proteolytic enzymes (plazmina, kinnoguenaza, trypsin, himotripsina) plasma, blood cells and tissues.IndicationsBleeding from giperfibrinolizom, incl. after surgeries and injuries; before, during and after childbirth; hemorrhagic complications arising from tromboliticescoy therapy, acute pancreatitis, preventing postoperative pancreatitis and fat embolism.Pregnancy and lactationContraindicated (I-trimester screening). At the time of treatment should stop breastfeeding.ContraindicationsГиперчувствительност ь.Side-EffectsFrom the circulatory system and blood (blood, gemostaz) : gipotenzia arterial and / or Tahikardia.so part of the intestine : nausea, Rvota.allergicakie reactions : allergic (skin rash) and anaphylacticskie (up to anaphylacticski shock) reaction.OverdosingNumerous tests conducted on various types of animals, even in the application of Aprotinin in doses much higher than therapeutic doses for people of any toxic effects have been detected.Dosing and AdministrationB / in (slow) struino or drip. Adult initial dose is 200000-300000 Atre, the 140,000-Atre every four hours before the normalization of hemostasis. When violations hemostasis in children agent appointed dose 14,000 Atre / kg / sut. The homemade solution for the on / in the dry substance dissolved in izotonicescom solution of sodium chloride in a ratio of one bad product : 1 USD solvent.Storage conditionsList B. Under normal circumstances,Shelf life3 yearsThe registration00124 (Ann.2001) |
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