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Daonil

See also Glibenclamide

Roman name

Daonil

The composition and the form of

1 tablet contains glibenklamida 5 mg; blistere in 10 pcs. , in a carton 3 and 5 blisters.

Pharmacokinetics

Well drawn from the blood (92%). C_max achieved through 2-6 hours Linking blood plasma by 99%. The distribution-10 litres. T_1/2 - 4-11 16a0 hours Metabolised in the liver. Excreted with jelchew and urine in the form of inactive metabolites.

Indications

Insulinnezawisimy diabetes (type II), in cases where the blood sugar levels are not adequate diet, exercise or lower body mass index.

Pregnancy and lactation

Counter (to be changed to insulin).

Contraindications

Hypersensitivity, insulinzawisimy diabetes mellitus (type I) in children and adolescents, the metabolic ketoacidosis expressed human liver and / or kidney.

Side-Effects

Hypoglycaemia, headache, dizziness, weakness, anaemia, eritropenia, lakopenia, allergic reactions.

Patient interaction

Prolongirovanne sulfanilamida, chloramphenicol, and tetratziklinove kumarinove derivatives, cyclophosphamide, MAO inhibitors increase gipoglikemiceski effect.

Precautions

Passes receiving regular dosage should not be compensated for hosting more doses.

Dosing and Administration

Dose prepared individually, depending on age, severity of the current diabetes, the level of glycemia. Average daily intake : 2.5 mg. Multiple admi fee5 ssion 1-2 times a day. The daily intake increased every 5-6 days to 2.5 mg to normalize blood glucose. Not recommended increasing doses above 15 mg / sut.

Storage conditions

List B. The temperature is not above 30 ° C

Shelf life

5 years

The registration

008,721 (Ann.2003)

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