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Diabeton

See also Gliclazide

Roman name

Diabeton

The composition and the form of

1 tablet contains gliklazida 80 mg; blistere in 30 pcs. , in a cardboard box two blisters.

Pharmacokinetics

Rapidly absorbed. C_max - 2-5 pm Linking plasma protein is 94.2%. T_1/2-12 p.m. Write memory (less than 1% in an unmodified form).

Farmakodinamika

Impact giperglikemia, oppressing and adhesion agregatia platelets, normalizes fibrinoliticescuu activity endotelia (Diabetic I and II type), normalizes blood pressure and prevent the formation of mikrotrombov; The антиатеросклеротичес ким effect.

Clinical pharmacology

Statistically reliable slows development diabetic retinopathy. Prolonged use of the ADA nefropatii does not alter renal function and accompanied by a decline in proteinurii, better control blood glucose and blood pressure. There is an increase in body mass index, on the other hand, helps to reduce the fat patients (subject to the diet); Not provoke giperinsulinemii.

Indications

Diabetes mellitus insulinnezawisimy.

Pregnancy and lactation

Contraindicated.

Contraindications

Hypersensitivity, incl. from other sulfamidam, youth diabetes, ketoacidosis, and prekomatosnye komatosnye state severe renal failure, severe liver failure.

Side-Effects

Diarrhoeal phenomenon (very rarely), hypoglycaemia, reversible hematologic violations, allergic reaction (itching, erythema, urticaria), rarely, in the form of light.

Specific guidance

To prevent dispepticakih events to take medication during mealtimes. It should not be undertaken simultaneously miconazole. The treatment does not exclude the need for nizkokalorina diet low-carbohydrates.

Patient interaction

The lower dioretiki and barbiturates increase-NPVS, sulfanilamida, beta-adrenoblokatora.

Overdosing

In the case of moderate gipoglikemii (malaise, sweat, paleness, tachycardia), a dose adjustment; In the most severe cases, the disorders of consciousness to be an on / in a gipertoniceski glucose solution (40%).

Precautions

It regularly determine the level of glucose in the blood erh, after meals and daily curve. "

Dosing and Administration

Inside. The batch is individually depending on the seriousness of the illness, as a rule, and 2 table per day (1 tab. morning and evening, at the time of delivery). Depending on the seriousness of the illness dose may be 1-4 table. per day.

Storage conditions

List B. The temperature is not above 30 ° C

Shelf life

3 years

The registration

015418/01

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