Directory → Metaboliki → Gipoglikemicakie synthetic and other means → Glibutid
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GlibutidSee also BuforminRoman nameGlibutidumThe composition and the form ofThe white crystalline powder bitter taste. Easily soluble in water and alcoholOf drugsIt stimulates the secretion of (a) insulin beta-kletkami islets Langergansa pancreas. High drug appointed when regulation of hydrocarbons to a diet and insulinproducyrute cells capable of secreting insulin.Storage conditionsList B. In the dark spot.Indications for useDespite d change for the treatment of diabetes mellitus type II (инсулинонеззвисимог��) in adults. In combination with insulin use in insulinorezistentnykh forms of diabetes (diabetes resistant to treatment with drugs insulin), and the resistance (resistance) to antidiabeticski drugs sulfonylureas, and netagelah forms of diabetes, obesity combined, and in patients receiving treatment with insulin, and over labilne diabetes (diabetes, characterized by rapid changes in blood sugar).Dosing and AdministrationGlikvidon has a wide range of therapeutic effects : from 1 / 2 tablets (15 mg) to 4 tablets (120 mg) a day. In normal cases, the average daily intake is 45 mg per day. Daily intake depends on the individual characteristics of the patients. However, the excess of a daily dose of four tablets (120 mg), as a rule, does not lead to further improvement of hydrocarbons. Daily glikvidona dose can be taken once for breakfast or divided into two reception hour food.Side-EffectsGlibutid well tolerated, but there was a loss of appetite, nausea, vomiting, diarrhoea (diarrhea), metallic taste in his mouth. At a later date from the beginning of treatment (a month or more) may be weak, reducing body weight.ContraindicationsRecommandations to the application glibutida are : absolute testimony to the use of insulin, the lack of body endogenous (produced in the body) or exogenous input (from) insulin, komatosnye condition (loss of consciousness, characterized by the complete absence of responses of the external stressors), acidosis (acidification), infectious diseases, albuminurija (protein in the urine) in the soil depends nefropatii (defeat receptacles and kidney tissues diabetes), lesion of the liver, diabetic angiopatia (the famous blood vessels associated with high blood sugar), with the possibility of inflammatory process, limb gangrene, pregnancy.Form ofAnswers to 0.05g in a package of 50 pieces. Pill extended (long-term) of buformin retard, containing 0.17 g buformina tosilata, which corresponds to 0.1 g of substance (glibutida). |
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