Gliformin

Roman name

Gliforminum

Of drugs

Oral (adopted by mouth) antidiabeticeski (reduction blood sugar) product from the group biguanidov. Mode of Action gipoglikemisirutego (reducing blood sugar) of the final is not clear. Suppress glukoneogenez (education glucose) in the liver activates glikoliz (fission process glucose), reduces the induction of glucose from the intestines. Apparently gliformin improves insulin binding to the receptor. The diabetics suffering from obesity, reduces appetite and reduces body weight. Has also fibrinoliticescoe Effects (dissolving blood bunch), reduces the adhesion (slipanie) platelets. The drug lowers the level of glucose (sugar) in the blood only in the management of diabetes mellitus and is not such an act of healthy individuals.

Storage conditions

List B. In a dry, the dark spot.

Indications for use

Insulinonezawisimy diabetes, especially if it is accompanied by obesity, without the ability to ketoatsidozu (banned because of the excess in the blood ketonovykh phone). Coupled with the use insulinoterapiei insulinozawisimom with diabetes; Insulinorezistentne (resistant to insulin action), diabetes (when the daily need for insulin than 200 U); Diabetes mellitus, rezistennetary (sustained) in the treatment of derivatives sulfonylureas.

Dosing and Administration

The preparation appoint two tablets (0.5 g), 2 times a day during or immediately after delivery for the first three days; In the subsequent two tablets three times a day. After 15 days from the start of treatment, depending on the level of glucose in the blood determine the individual dose for each patient. Usually supporting dose of 2-4 tablets a day. Do not exceed the dose of more than 3 grams (6 tablets) a day.

Side-Effects

Nausea, vomiting, diarrhea, metallic taste in the mouth, skin rashes. With long-term use drugs may breach in the upper gastrointestinal tract vitamin Vp.

Contraindications

Prekomatosnye state (partial loss of consciousness, the initial stage of coma characterized by continuing pain and Reflective reactions); Diabetic (associated with high blood sugar) coma (complete loss of consciousness, characterized by the complete absence of responses of the external stressors) and ketonovy acidosis (acidification due to the excessive content in the blood ketonovykh tel); gipoglikemical (associated with a sharp drop in blood sugar) coma. Lactate acidosis (acidification due to the high level of lactic acid), including history (formerly earlier); State, in which elevated risk of a (pulmonary insufficiency, shock, heart failure, myocardial infarction). Heavy forms of kidney failure; Chronic liver disease. Pregnancy. The period before the surgery, and two days after the operation.

Form of

Answers to 0.25, or 0.5 g per pack of 50 pieces; Retard tablets of 0.85 grams per pack to 10 pieces.

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